1-Adamantanol 768-...

1-Adamantanol  768-95-6
1-Adamantanol  768-95-6
1-Adamantanol  768-95-6

1-Adamantanol 768-95-6

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100 Kilogram

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  • Min.Order :100 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

RARECHEM AH PB 0251 768-95-6 C10H16O

Quick Details

  • Appearance:powder
  • Application:768-95-6
  • PackAge:Depended
  • ProductionCapacity:300|Kilogram|Month
  • Storage:Refrigerator
  • Transportation:by air or by sea

Superiority:

1-Adamantanol Basic information
Outline Application
Product Name: 1-Adamantanol
Synonyms: TRICYCLO[3.3.1.1(3,7)]DECAN-1-OL;TRICYCLO[3.3.1.1]DECAN-1-OL;1-Adamantol;1-Adamatanol;-Adamantyl alcohol;damantol-(1);tricyclo(3.3.1.1(sup3,7))decan-1-ol;1-HYDROXYDIAMANTANE
CAS: 768-95-6
MF: C10H16O
MW: 152.23
EINECS: 212-202-8
Product Categories: Pharmaceutical Raw Materials;Adamantane Derivative;FINE Chemical & INTERMEDIATES;Adamantane derivatives;Adamantanes;Alcohols;Building Blocks;C9 to C10;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
Mol File: 768-95-6.mol
1-Adamantanol Structure
 
1-Adamantanol Chemical Properties
mp  247 °C (subl.)(lit.)
Fp  240°C
storage temp.  2-8°C
Sublimation  240 ºC
BRN  1903952
CAS DataBase Reference 768-95-6(CAS DataBase Reference)
NIST Chemistry Reference 1-Adamantanol(768-95-6)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36-26
WGK Germany  3
RTECS  AU4980000
Hazard Note  Irritant
HS Code  29061900
MSDS Information
Provider Language
1-Hydroxyadamantane English
ACROS English
SigmaAldrich English
ALFA English
 
1-Adamantanol Usage And Synthesis
Outline 1-adamantanol is also known as 1- hydroxide adamantane, 1-tricyclo [3.3.1.1 (3.7)] decyl alcohol. At room temperature, it is white crystalline powder with the melting point higher than 240 ℃. It is soluble in organic solvents and insoluble in water with sublimation property. It can be used for the manufacture of synthetic adamantane derivatives and adapalene. It can react with vinylidene chloride to generate 1- adamantane acetic acid. 1-adamantyl acetate can further undergo bromination and hydrolyzed into 3-hydroxy-1-adamantyl acetate which can further react with vinylidene chloride to give 1, 3-adamantane di-acetic acid. 
1-adamantanol can have Friedel-Crafts alkylation reaction acetanilide in the 98% sulfuric acid medium at room temperature for direct synthesis of 1, 3-bis (4-acetylamino-phenyl) adamantane which can undergo alkaline hydrolysis for synthesis of 1, 3 bis (4-aniline) adamantane. The synthetic route has many advantages including relative high reaction yield and easy purification, etc., therefore greatly facilitating the synthesis of 1, 3-diaryl adamantane derivatives. 
The above information is edited by the Chemicalbook of Dai Xiongfeng.
Application 1-adamantanol can be used as the intermediate for synthesis of adamantanes derivatives. For example, it can be used for the manufacture of synthetic adamantane derivatives and adapalene. It can react with vinylidene chloride to give 1- adamantane acetic acid.
Chemical Properties white to off-white crystalline powder or needles
 
 
 

 

 

 

 

 

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