Omeprazole 73590-58-6 belmazol;ceprandal;elgam
Omeprazole Chemical Properties |
mp | 156°C |
storage temp. | 2-8°C |
solubility | H2O: 0.5 mg/mL |
form | solid |
color | white |
Merck | 6845 |
Stability: | Stable, but hygroscopic and photosensitive. Incompatible with strong oxidizing agents. Store in the dark. |
CAS DataBase Reference | 73590-58-6(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xi,T,F |
Risk Statements | 36/37/38-39/23/24/25-23/24/25-11 |
Safety Statements | 26-36-37/39-45-36/37-16-7 |
WGK Germany | 2 |
RTECS | DD9087000 |
Hazardous Substances Data | 73590-58-6(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
5-Methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H-benzoimidazole | English |
SigmaAldrich | English |
Omeprazole Usage And Synthesis |
Chemical Properties | White Crystalline Solid |
Usage | Binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative |
Usage | diuretic, sweetener, diagnostic aid |
Usage | A selective proton pump and CYP inhibitor |
Usage | Omeprazole Pellets are used in the treatment of Gastroesophageal reflux disease (GERD): A condition in which backward flow of acid from the stomach causes heartburn and injury of the food pipe (esophagus) |
Biological Activity | H + ,K + -ATPase inhibitor (IC 50 = 5.8 μ M) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC 50 = 0.16 μ M for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacteral against Helicobacter pylori in vitro . Also inhibits CYP2C19, CYP2C9 and CYP3A (K i values are 3.1, 40.1 and 84.4 μ M respectively) and blocks swelling-dependent chloride channels (ICIswell). |
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