CHLORAL HYDRATE 2-ethanediol TRICHLOROACETALDEHYDE HYDRATE
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2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)
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Product Name: | Chloral hydrate |
Synonyms: | CHLORAL HYDRATE;'GROUND JOINT SEPARATION AID';1,1,1-trichloro-2,2-ethanediol;2,2,2-Trichloro-1,1-ethanediol;2,2,2-TRICHLOROETHANE-1,1-DIOL;2,2,2-TRICHLOROETHANE-1,1-DIOL HYDRATE;TRICHLOROACETALDEHYDE HYDRATE;TRICHLOROACETALDEHYDE MONOHYDRATE |
CAS: | 302-17-0 |
MF: | C2H3Cl3O2 |
MW: | 165.4 |
EINECS: | 206-117-5 |
Product Categories: | Miscellaneous;Organics;Method 551EPA;Method 8240;500 Series Drinking Water Methods;8000 Series Solidwaste Methods;EPA;Aldehydes;Bioactive Small Molecules;Building Blocks;C1 to C6;Carbonyl Compounds;C-CH;Cell Biology;Chemical Synthesis;Organic Building Blocks |
Mol File: | 302-17-0.mol |
Chloral hydrate Chemical Properties |
mp | 57 °C(lit.) |
bp | 97 °C |
density | 1.43 g/mL at 20 °C |
Fp | 16 °C |
storage temp. | 0-6°C |
Water Solubility | 660 g/100 mL |
Merck | 13,2080 |
Stability: | Stable, but may be air or light sensitive. Incompatible with alcohols, cyanides, iodine, strong bases, carbonates. |
CAS DataBase Reference | 302-17-0(CAS DataBase Reference) |
NIST Chemistry Reference | Chloral hydrate(302-17-0) |
EPA Substance Registry System | 1,1-Ethanediol, 2,2,2-trichloro-(302-17-0) |
Safety Information |
Hazard Codes | T,F,Xn |
Risk Statements | 25-36/38-39/23/24/25-23/24/25-11-36/37/38-36-20/21/22 |
Safety Statements | 26-45-25-23-36/37-16-27 |
RIDADR | UN 3286 3/PG 2 |
WGK Germany | 2 |
RTECS | FM8750000 |
HazardClass | 6.1(b) |
PackingGroup | III |
Hazardous Substances Data | 302-17-0(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
ACROS | English |
Chloral hydrate Usage And Synthesis |
Chemical Properties | colourless crystals with a pentrating odour |
Usage | Trichloroacetaldehyde Hydrate is a useful chemical reagent used as a sedative/hypnotic agent. Studies have shown that when used in pediatric sedation side effects such as hallucination, excessive slee p and seizures were observed. It is sometimes administered to patients being treated with cyclophosphamide and it is known to inhibit some aldehyde dehydrogenases. |
General Description | Transparent colorless crystals or white crystalline solid. Aromatic penetrating slightly acrid odor and a slightly bitter caustic taste. Alcoholic solution (1 in 20) does not at once redden moistened blue litmus paper. |
Air & Water Reactions | Water soluble. |
Reactivity Profile | Chloral hydrate is incompatible with alkalis, alkaline earth metals, alkali carbonates and soluble barbiturates. Chloral hydrate is decomposed by sodium hydroxide. Chloral hydrate reduces ammoniacal silver nitrate. Chloral hydrate liquefies when triturated with an equal quantity of menthol, camphor or thymol. . Reaction of Chloral hydrate with hydroxylamine produces toxic hydrogen cyanide gas, Org. Synth., 1941, Vol. 1, 377. |
Fire Hazard | Flash point data for Chloral hydrate are not available; however, Chloral hydrate is probably combustible. |
Chloral hydrate Preparation Products And Raw materials |
Preparation Products | Chloral-->Trichloroacetic acid-->5-Methoxy-3-indazolecarboxylic acid-->1,2,3,4-TETRAHYDRO-9-ACRIDINAMINE-->TENIDAP-->5-Methoxyisatin-->6-Bromoisatin-->2-AMINO-5,6-DICHLOROBENZOIC ACID-->Etodolac |
Raw materials | Etanol-->Chlorine-->Calcium carbonate-->Hydroquinone-->Chloral |
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