CAS:555-30-6 C10H13...

CAS:555-30-6 C10H13NO4 Methyldopa

CAS:555-30-6 C10H13NO4 Methyldopa

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CAS:555-30-6 C10H13NO4 Methyldopa CAS:555-30-6 C10H13NO4 CAS:555-30-6

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  • Application:CAS:555-30-6 C10H13NO4 Methyldopa
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Methyldopa Basic information
Product Name: Methyldopa
Synonyms: MK-351;L-(-)-ALPHA-METHYLDOPA;L-ALPHA-METHYL-DOPA;L-3-(3,4-DIHYDROXYPHENYL)-2-METHYLALANINE;MEDOBA;L-METHYLDOPA;METHYL DOPA;METHYL-L-DOPA
CAS: 555-30-6
MF: C10H13NO4
MW: 211.21
EINECS: 209-089-2
Product Categories: API's;Aldomet;RUBRAMIN
Mol File: 555-30-6.mol
Methyldopa Structure
 
Methyldopa Chemical Properties
mp  ≥300 °C
refractive index  -14 ° (C=1, H2O)
storage temp.  Store at RT
Merck  6055
CAS DataBase Reference 555-30-6(CAS DataBase Reference)
EPA Substance Registry System L-Tyrosine, 3-hydroxy-.alpha.-methyl-(555-30-6)
 
Safety Information
WGK Germany  3
RTECS  YP2860000
10-23
Hazardous Substances Data 555-30-6(Hazardous Substances Data)
MSDS Information
 
Methyldopa Usage And Synthesis
Usage Antihypertensor;L-aromatic aminoacid decarboxylase inhibitor
Usage vitamin, coenzyme B12
General Description Colorless or almost colorless crystals or white to yellowish-white fine powder. Almost tasteless. In the sesquihydrate form. pH (saturated aqueous solution) about 5.0.
Air & Water Reactions Very hygroscopic. Slightly water soluble. May be sensitive to prolonged exposure to air and light. The stability of aqueous solutions is markedly dependent on pH, oxygen and the amount of initial reactant. Aqueous solutions are stable for up to 50 hours in acid and neutral pH (6.2). At pH 8.0, decomposition products are formed in 3 to 5 hours. Solutions develop a red tint that becomes progressively darker (eventually forming a black precipitate).
Reactivity Profile Methyldopa undergoes catalytic oxygenation in the presence of magnesium, cupric, cobalt, nickel and ferric ions . A weakly acidic amino acid.
Fire Hazard Flash point data for Methyldopa are not available; however, Methyldopa is probably combustible.
Biological Activity L-aromatic amino acid decarboxylase inhibitor. Antihypertensive.
 
Methyldopa Preparation Products And Raw materials
Raw materials Dimethyl sulfate-->Vanillin-->Anisole-->Nitroethane-->Veratraldehyde-->3,4-Dimethoxyphenylacetone-->3-Hydroxy-alpha-methyl-DL-tyrosine

 

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