RARECHEM AH PB 0251 113507-06-5 C37H53NO8
Moxidectin Basic information |
Product Name: | Moxidectin |
Synonyms: | Moxidectin;Milbemycin B, 5-O-demethyl-28-deoxy-25-(1E)-1,3-dimethyl-1-butenyl-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-;proheart;(6R,23E,25S)-5-O-DeMethyl-28-deoxy-25-[(1E)-1,3-diMethyl-1-buten-1-yl]-6,28-epoxy-23-(MethoxyiMino)MilbeMycin B;[6R,23E,25S(E)]-5-O-DeMethyl-28-deoxy-25-(1,3-diMethyl-1-butenyl)-6,28-epoxy-23-(MethoxyiMino)MilbeMycin B;23-MethoxiMe-LL-F 28249α;Equest;ProHeart 6 |
CAS: | 113507-06-5 |
MF: | C37H53NO8 |
MW: | 639.825 |
EINECS: | |
Product Categories: | Anthelmintic, antiparasitic.;METI - MZAntibiotics;MLSAnalytical Standards;Antibiotics;BacteriostaticAntibiotics;beta-Lactam StructureAlphabetic;Chemical Structure;Chromatography;M;Pharmacology Standards;Principle;CYDECTIN |
Mol File: | 113507-06-5.mol |
Moxidectin Chemical Properties |
storage temp. | 2-8°C |
Safety Information |
Hazard Codes | T,N |
Risk Statements | 25-50 |
Safety Statements | 45-61 |
RIDADR | 2588 |
HazardClass | 6.1(b) |
PackingGroup | III |
Moxidectin Usage And Synthesis |
Usage | anthelmintic, antiparasitic |
Usage | Moxidectin is a macrocyclic lactone and semisynthetic derivative of nemadectin. Moxidectin is a parasiticide used for the prevention and control of heartworm and intestinal worms. Moxidectin is is fou nd in veterinary medicine used to treat animals such as dogs, cats, horses, cattle and sheep. |
Usage | Moxidectin is a semi-synthetic milbemycin derived from nemadectin by selective oxidation followed by methyloximation. Moxidectin was patented in 1991 as an anthelmintic for internal parasite control. The presence of the methyloxime affords moxidectin a greater hydrophobicity and longer biological half-life compared to nemadectin. Moxidectin binds selectively to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite. |
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