CAS:135062-02-1 C27H36N2O4 Repaglinide CAS:135062-02-1 C27H36N2O4 CAS:135062-02-1
Repaglinide Basic information |
Product Name: | Repaglinide |
Synonyms: | AG-EE-623;2-ETHOXY-4-[2-[(1S)-3-METHYL-1-[2-(1-PIPERIDINYL)BUTYL]AMINO]-2-OXOETHYL]-BENZOIC ACID;REPAGLINIDE;(S)-2-ETHOXY-4-(2-(3-METHYL-1-(2-(PIPERIDIN-1-YL)PHENYL)BUTYLAMINO)-2-OXOETHYL)BENZOIC ACID;(S)-(+)-2-ETHOXY-4-[N-[1-(2-PIPERIDINOPHENYL)-3-METHYL-1-BUTYL]AMINOCARBONYLMETHYL]BENZOIC ACID;NOVONORM;PRANDIN;ag-ee388zw |
CAS: | 135062-02-1 |
MF: | C27H36N2O4 |
MW: | 452.59 |
EINECS: | |
Product Categories: | Pharmaceutical material and intermeidates;Active Pharmaceutical Ingredients;Chiral Reagents;Amino Acids 13C, 2H, 15N;Chemical Impurities;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Amino Acids & Derivatives;Aromatics;Heterocycles;API;Pharmaceutical raw material;DTIC-DOME |
Mol File: | 135062-02-1.mol |
Repaglinide Chemical Properties |
mp | 129-130.2 °C |
storage temp. | 2-8°C |
solubility | DMSO: 34 mg/mL |
form | solid |
color | white |
CAS DataBase Reference | 135062-02-1(CAS DataBase Reference) |
Safety Information |
WGK Germany | 2 |
RTECS | 000000033825 |
MSDS Information |
Provider | Language |
---|---|
Novonorm | English |
SigmaAldrich | English |
Repaglinide Usage And Synthesis |
Chemical Properties | White to Off-White Solid |
Usage | Non-sulfonylurea oral hypoglycemic agent. Used as an antidiabetic |
Usage | The R-enantiomer showed only weak hypoglycemic activity. Repaglinide impurity |
Usage | antineoplastic |
Usage | A KIR6 (KATP) channel blocker |
Biological Activity | K ATP channel blocker that binds with high affinity for SUR1 when co-expressed with Kir6.2 (K d = 0.42 nM). Antidiabetic glucose regulator with hypoglycaemic effect in vivo . |
Repaglinide Basic information |
Product Name: | Repaglinide |
Synonyms: | AG-EE-623;2-ETHOXY-4-[2-[(1S)-3-METHYL-1-[2-(1-PIPERIDINYL)BUTYL]AMINO]-2-OXOETHYL]-BENZOIC ACID;REPAGLINIDE;(S)-2-ETHOXY-4-(2-(3-METHYL-1-(2-(PIPERIDIN-1-YL)PHENYL)BUTYLAMINO)-2-OXOETHYL)BENZOIC ACID;(S)-(+)-2-ETHOXY-4-[N-[1-(2-PIPERIDINOPHENYL)-3-METHYL-1-BUTYL]AMINOCARBONYLMETHYL]BENZOIC ACID;NOVONORM;PRANDIN;ag-ee388zw |
CAS: | 135062-02-1 |
MF: | C27H36N2O4 |
MW: | 452.59 |
EINECS: | |
Product Categories: | Pharmaceutical material and intermeidates;Active Pharmaceutical Ingredients;Chiral Reagents;Amino Acids 13C, 2H, 15N;Chemical Impurities;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Amino Acids & Derivatives;Aromatics;Heterocycles;API;Pharmaceutical raw material;DTIC-DOME |
Mol File: | 135062-02-1.mol |
Repaglinide Chemical Properties |
mp | 129-130.2 °C |
storage temp. | 2-8°C |
solubility | DMSO: 34 mg/mL |
form | solid |
color | white |
CAS DataBase Reference | 135062-02-1(CAS DataBase Reference) |
Safety Information |
WGK Germany | 2 |
RTECS | 000000033825 |
MSDS Information |
Provider | Language |
---|---|
Novonorm | English |
SigmaAldrich | English |
Repaglinide Usage And Synthesis |
Chemical Properties | White to Off-White Solid |
Usage | Non-sulfonylurea oral hypoglycemic agent. Used as an antidiabetic |
Usage | The R-enantiomer showed only weak hypoglycemic activity. Repaglinide impurity |
Usage | antineoplastic |
Usage | A KIR6 (KATP) channel blocker |
Biological Activity | K ATP channel blocker that binds with high affinity for SUR1 when co-expressed with Kir6.2 (K d = 0.42 nM). Antidiabetic glucose regulator with hypoglycaemic effect in vivo . |
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