mebendazole (MBZ) 31431-39-7 antihelminthic agent?
Mebendazole (MBZ) is a medication used to treat a number of parasitic worm infestations.This includes ascariasis, pinworm disease, hookworm infections, guinea worm infections, hydatid disease, and giardia, among others. It is taken by mouth.
Mebendazole is usually well tolerated.Common side effects include headache, vomiting, and ringing in the ears. If used at large doses it may cause bone marrow suppression. It is unclear if it is safe in pregnancy.Mebendazole is a broad-spectrum antihelminthic agent of thebenzimidazole type.
Mebendazole came into use in 1971.It is included in the WHO Model List of Essential Medicines, the most important medications needed in a basichealth system.Mebendazole is available as a generic medication.
product Name |
mebendazole |
Synonyms |
methyl 5-benzoylbenzimidazol-2-ylcarbamate; methyl 5-benzoylbenzimidazole-2-carbamate; methyl (6-benzoyl-1H-benzimidazol-2-yl)carbamate |
Molecular Formula |
C16H13N3O3 |
Molecular Weight |
295.2927 |
InChI |
InChI=1/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21) |
CAS Registry Number |
31431-39-7 |
EINECS |
250-635-4 |
Molecular Structure |
|
Density |
1.388g/cm3 |
Melting point |
288.5℃ |
Refractive index |
1.702 |
Hazard Symbols |
|
Risk Codes |
R22:; |
Safety Description |
S36:; |
Content |
99.0% ~ 101.0% |
Appearance |
White or almost white powder |
Solubility |
Practically insoluble in water, in alcohol and in methylene chloride. It shows polymorphism. |
Identification |
IR: Correspond with CRS |
Related substances |
Impurity G: not more than 0.5% |
|
Any other impurity: not more than 0.25% |
|
Total impurities: not more than 1.0% |
|
Disregard limit: not more than 0.05% |
Loss on drying |
Maximum 0.5% |
Sulphated ash |
Maximum 0.1% |
Storage |
Protected from light |
CAS NO:18472-51-0
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CAS NO:6091-44-7
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