CAS:152520-56-4 C22H26ClF2NO4 Nebivolol hydrochloride
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| 500 Gram |
Negotiable |
- Min.Order :500 Gram
- Purity: 99%
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Keywords
C22H26ClF2NO4 CAS:152520-56-4 C22H26ClF2NO4 Nebivolol hydrochloride CAS:152520-56-4
Quick Details
- Appearance:white poweder
- Application:CAS:152520-56-4 C22H26ClF2NO4 Nebivolol hydrochloride
- PackAge:Plastic vacuum packaging bag or bucket
- ProductionCapacity:1|Metric Ton|Day
- Storage:under the cool and dry area
- Transportation:by express or by sea
Superiority:
| Nebivolol hydrochloride Basic information |
| Product Name: | Nebivolol hydrochloride |
| Synonyms: | RAC NEBIVOLOL, HYDROCHLORIDE;a,a(Iminodimethylene)bis[6-fluoro-2-chromanmethanol] Hydrochloride;Lobivon;Nebilet;Nebilox;R-67555;NEBIVOLOLHYDROCHLORIDE(SUBJECTTOPATENTFREE);a,a'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol hydrochloride |
| CAS: | 152520-56-4 |
| MF: | C22H26ClF2NO4 |
| MW: | 441.9 |
| EINECS: | |
| Product Categories: | Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API;R-67145 |
| Mol File: | Mol File |
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| Nebivolol hydrochloride Chemical Properties |
| mp | 220-222°C |
| storage temp. | Desiccate at RT |
| Nebivolol hydrochloride Usage And Synthesis |
| Chemical Properties | White to Off-White Powder |
| Usage | A -Adrenergic blocker. Used as an antihypertensive |
| Usage | Nebivolol selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM |
| Biological Activity | Highly selective β 1 -adrenoceptor antagonist (K i values are 0.88, 20, 44, 700, 1160, 2400 and 4000 nM at β 1 , 5-HT 1A , β 2 , 5-HT 2 , α 1 , H 1 and D 2 receptors respectively). Induces vasodilation via a nitric oxide- and cGMP-dependent mechanism (EC 50 = 11.36 μ M in renal arteries) and displays antihypertensive activity in vivo . |
Details:
| Nebivolol hydrochloride Basic information |
| Product Name: | Nebivolol hydrochloride |
| Synonyms: | RAC NEBIVOLOL, HYDROCHLORIDE;a,a(Iminodimethylene)bis[6-fluoro-2-chromanmethanol] Hydrochloride;Lobivon;Nebilet;Nebilox;R-67555;NEBIVOLOLHYDROCHLORIDE(SUBJECTTOPATENTFREE);a,a'-[Iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol hydrochloride |
| CAS: | 152520-56-4 |
| MF: | C22H26ClF2NO4 |
| MW: | 441.9 |
| EINECS: | |
| Product Categories: | Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API;R-67145 |
| Mol File: | Mol File |
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|
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| Nebivolol hydrochloride Chemical Properties |
| mp | 220-222°C |
| storage temp. | Desiccate at RT |
| Nebivolol hydrochloride Usage And Synthesis |
| Chemical Properties | White to Off-White Powder |
| Usage | A -Adrenergic blocker. Used as an antihypertensive |
| Usage | Nebivolol selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM |
| Biological Activity | Highly selective β 1 -adrenoceptor antagonist (K i values are 0.88, 20, 44, 700, 1160, 2400 and 4000 nM at β 1 , 5-HT 1A , β 2 , 5-HT 2 , α 1 , H 1 and D 2 receptors respectively). Induces vasodilation via a nitric oxide- and cGMP-dependent mechanism (EC 50 = 11.36 μ M in renal arteries) and displays antihypertensive activity in vivo . |
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