CAS:363-24-6 C20H32O5 Prostaglandin E2 CAS:363-24-6 C20H32O5 CAS:363-24-6
Prostaglandin E2 Basic information |
Product Name: | Prostaglandin E2 |
Synonyms: | DINOPROSTONE;9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID;7-[3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic acid;(5Z,11A,13E,15S)-11,15-DIHYDROXY-9-OXO-PROSTA-5,13-DIEN-1OIC ACID;[5Z,11ALPHA,13E,15S]-11,15-DIHYDROXY-9-OXOPROSTA-5,13-DIEN-1-OIC ACID;[5Z,11ALPHA,13E,15S]-11,15-DIHYDROXY-9-OXOPROSTA-5,13-DIENOIC ACID;PROSTAGLANDIN;PROSTAGLANDIN E2 |
CAS: | 363-24-6 |
MF: | C20H32O5 |
MW: | 352.47 |
EINECS: | 206-656-6 |
Product Categories: | Prostaglandins;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals |
Mol File: | 363-24-6.mol |
Prostaglandin E2 Chemical Properties |
mp | 66-68 °C |
alpha | -85.5 º (c=1, C2H5OH) |
storage temp. | −20°C |
solubility | ethanol: 1 mg/mL |
form | powder |
Water Solubility | insoluble |
Merck | 13,7969 |
CAS DataBase Reference | 363-24-6(CAS DataBase Reference) |
Safety Information |
Hazard Codes | T |
Risk Statements | 60-22-61 |
Safety Statements | 53-22-26-36/37/39-45 |
WGK Germany | 3 |
RTECS | UK8000000 |
F | 8-10 |
MSDS Information |
Provider | Language |
---|---|
PGE2 | English |
SigmaAldrich | English |
ACROS | English |
Prostaglandin E2 Usage And Synthesis |
Chemical Properties | White to pale yellowish-cream powder |
Usage | The most common and most biologically potent of mammalian prostaglandins. Isolated from sheep prostate. Oxytocic; abortifacient. |
Biological Activity | Endogenous prostaglandin and primary product of arachidonic acid/cyclooxygenase pathway. Binds with high affinity to EP 1 , EP 2 , EP 3 and EP 4 receptors (K d values range between ~ 1-10 nM). Influences a wide range of processes including inflammation, smooth muscle relaxation, fertility and gastric mucosal integrity. Regulates vertebrate hematopoietic stem cell (HSC) homeostasis. |
Prostaglandin E2 Preparation Products And Raw materials |
Raw materials | Hydrogen-->Potassium chloride -->Citric acid monohydrate-->Arachidonic acid-->Glutathione |
Preparation Products | Prostaglandin E1 |
Prostaglandin E2 Basic information |
Product Name: | Prostaglandin E2 |
Synonyms: | DINOPROSTONE;9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID;7-[3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic acid;(5Z,11A,13E,15S)-11,15-DIHYDROXY-9-OXO-PROSTA-5,13-DIEN-1OIC ACID;[5Z,11ALPHA,13E,15S]-11,15-DIHYDROXY-9-OXOPROSTA-5,13-DIEN-1-OIC ACID;[5Z,11ALPHA,13E,15S]-11,15-DIHYDROXY-9-OXOPROSTA-5,13-DIENOIC ACID;PROSTAGLANDIN;PROSTAGLANDIN E2 |
CAS: | 363-24-6 |
MF: | C20H32O5 |
MW: | 352.47 |
EINECS: | 206-656-6 |
Product Categories: | Prostaglandins;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals |
Mol File: | 363-24-6.mol |
Prostaglandin E2 Chemical Properties |
mp | 66-68 °C |
alpha | -85.5 º (c=1, C2H5OH) |
storage temp. | −20°C |
solubility | ethanol: 1 mg/mL |
form | powder |
Water Solubility | insoluble |
Merck | 13,7969 |
CAS DataBase Reference | 363-24-6(CAS DataBase Reference) |
Safety Information |
Hazard Codes | T |
Risk Statements | 60-22-61 |
Safety Statements | 53-22-26-36/37/39-45 |
WGK Germany | 3 |
RTECS | UK8000000 |
F | 8-10 |
MSDS Information |
Provider | Language |
---|---|
PGE2 | English |
SigmaAldrich | English |
ACROS | English |
Prostaglandin E2 Usage And Synthesis |
Chemical Properties | White to pale yellowish-cream powder |
Usage | The most common and most biologically potent of mammalian prostaglandins. Isolated from sheep prostate. Oxytocic; abortifacient. |
Biological Activity | Endogenous prostaglandin and primary product of arachidonic acid/cyclooxygenase pathway. Binds with high affinity to EP 1 , EP 2 , EP 3 and EP 4 receptors (K d values range between ~ 1-10 nM). Influences a wide range of processes including inflammation, smooth muscle relaxation, fertility and gastric mucosal integrity. Regulates vertebrate hematopoietic stem cell (HSC) homeostasis. |
Prostaglandin E2 Preparation Products And Raw materials |
Raw materials | Hydrogen-->Potassium chloride -->Citric acid monohydrate-->Arachidonic acid-->Glutathione |
Preparation Products | Prostaglandin E1 |
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