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TIANFU-CHEM 923564-51-6 ABT 263

TIANFU-CHEM 923564-51-6 ABT 263

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Keywords

923564-51-6 ABT 263 C47H55ClF3N5O6S3

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  • Application:923564-51-6
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  • ProductionCapacity:1|Metric Ton|Day
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Details:

ABT 263 Basic information
Product Name: ABT 263
Synonyms: 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide;ABT 263;Benzamide, 4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl)methyl)-1-piperazinyl)-N-((4-(((1R)-3-(4-morpholinyl)-1-((phenylthio)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)-;ABT-263,Navitoclax;Navitoclax;BenzaMide, 4-(4-((2-(4-chlorophenyl)-5,5-diMe;Navitoclax (ABT-263);(S)-4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((4-morpholino-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide
CAS: 923564-51-6
MF: C47H55ClF3N5O6S3
MW: 974.61
EINECS:  
Product Categories: Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Apis;Inhibitor
Mol File: 923564-51-6.mol
ABT 263 Structure
 
ABT 263 Chemical Properties
mp  114-116°C
storage temp.  -20°C Freezer, Under Inert Atmosphere
 
Safety Information
MSDS Information
 
 
ABT 263 Usage And Synthesis
Chemical Properties Pale Yellow Solid
Usage ABT-263 (Navitoclax) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤ 1 nM, respectively.
Usage A novel inhibitor of antiapoptotic BCL-2 proteins; a new promising anticancer drug candidate.
 
ABT 263 Preparation Products And Raw materials

 

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