CasNo.86639-52-3,86639-52-3,(86639-52-3) Suppliers

100 Kilogram	Negotiable

Min.Order :100 Kilogram
Purity: 99%
Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

RARECHEM AH PB 0251 86639-52-3 C22H20N2O5

Quick Details

Appearance:powder
Application:86639-52-3
PackAge:Depended
ProductionCapacity:300|Kilogram|Month
Storage:Refrigerator
Transportation:by air or by sea

Superiority:

7-Ethyl-10-hydroxycamptothecin Basic information

Product Name:	7-Ethyl-10-hydroxycamptothecin
Synonyms:	CAMPTOTHECIN, 7-ETHYL-10-HYDROXY;4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;7-ETHYL-10-HYDROXYCAMPTOTHECIN;7-ETHYL-10-HYDROXYCAMPTOTHECINE;7-ETHYL-10-HYDROXY-CPT;SN38;10-dihydroxy-;4’:6,7)indolizino(1,2-b)quinoline-3,14(4h,12h)-dione,4,7-diethyl-1h-pyrano(3
CAS:	86639-52-3
MF:	C22H20N2O5
MW:	392.4
EINECS:
Product Categories:	Pharmaceutical Raw Materials;Miscellaneous Natural Products;Antitumors for Research and Experimental Use;Biochemistry;Natural Plant Extract;Chiral Reagents;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Natural Anti-cancer Medical Materials and It's Derivatives;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Inhibitors
Mol File:	86639-52-3.mol

7-Ethyl-10-hydroxycamptothecin Chemical Properties

mp	217 °C
refractive index	21.5 ° (C=0.2, THF)
storage temp.	−20°C
CAS DataBase Reference	86639-52-3(CAS DataBase Reference)

Safety Information

Hazard Codes	T
Risk Statements	25
Safety Statements	45
RTECS	UQ0491000

MSDS Information

7-Ethyl-10-hydroxycamptothecin Usage And Synthesis

Chemical Properties	Light-Yellow Solid
Usage	A metabolite of Irinotecan, a DNA topoisomerase inhibitor
Biological Activity	Active metabolite of CPT-11 that inhibits DNA topoisomerase I (IC 50 values are 0.74 and 1.9 μ M in P388 and Ehrlich cells respectively). Inhibits DNA and RNA synthesis (IC 50 values are 0.077 and 1.3 μ M respectively) but does not affect protein synthesis. Displays potent antitumor activity against a range of human tumor cell lines (IC 50 values are 3.3, 13, 19 and 22 nM for HCT-116, BEL-7402, HL60 and HELA cells respectively).

7-Ethyl-10-hydroxycamptothecin Preparation Products And Raw materials

Preparation Products

Irinotecan

Service we provide:

1. Mixed container, we can mix different items in one container.

2. Quality control, before shipment, free sample for test. after shipment, keep sample for 3 years

3. Prompt shipment with professional documents

4. Packing as your request, with photo before shipment

Details:

Exhibition in shanghai

We have clients throughout the world：

Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet your desire.

Our Laboratoy

We have our own independent lab test center：

This makes sure that our technology support is reliable and authoritative.All of self-owned fine chemicals are manufactured strictly in accordance with international standard.,and also has scientific cooperation with local colleges and institutes.