- Min.Order :1 Kilogram
- Purity: 99.0%
- Payment Terms : L/C,T/T
Keywords
938440-64-3 KU-0063794 KU-0063794
Quick Details
- Appearance:white powder
- Application:For organic use
- PackAge:as clients needs
- ProductionCapacity:10|Metric Ton|Month
- Storage:Room temperature
- Transportation:AS PER MSDS
Superiority:
| KU-0063794 Basic information |
| Product Name: | KU-0063794 |
| Synonyms: | BENZENEMETHANOL, 5-[2-[(2R,6S)-2,6-DIMETHYL-4-MORPHOLINYL]-4-(4-MORPHOLINYL)PYRIDO[2,3-D]PYRIMIDIN-7-YL]-2-METHOXY-, REL-;KU0063794;5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol;(5-(2-((2R,6S)-2,6-Dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol;rel-5-[2-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol;KU0063794(KU63794);KU-0063794(KU 0063794);BENZENEMETHANOL, 5-[2-[(2R,6S)-2,6-DIMETHYL-4-MORPHOLINYL]-4-(4-MORPHOLINYL)PYRIDO[2,3-D]PYRIMIDIN-7 |
| CAS: | 938440-64-3 |
| MF: | C25H31N5O4 |
| MW: | 465.551 |
| EINECS: | |
| Product Categories: | Inhibitors |
| Mol File: | 938440-64-3.mol |
|
|
|
| KU-0063794 Chemical Properties |
| density | 1.248 |
| storage temp. | Store at RT |
| KU-0063794 Usage And Synthesis |
| Biological Activity | Selective inhibitor of mammalian target of rapamycin (mTOR) (IC 50 ~10 nM for mTORC1 and mTORC2 respectively). Displays no activity at PI 3-kinase or 76 other kinases tested. Inhibits activation and hydrophobic motif phosphorylation of Akt, S6K and SGK, but not RSK. Suppresses cell growth and induces G 1 cell cycle arrest in vitro . |
Details:
| KU-0063794 Basic information |
| Product Name: | KU-0063794 |
| Synonyms: | BENZENEMETHANOL, 5-[2-[(2R,6S)-2,6-DIMETHYL-4-MORPHOLINYL]-4-(4-MORPHOLINYL)PYRIDO[2,3-D]PYRIMIDIN-7-YL]-2-METHOXY-, REL-;KU0063794;5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol;(5-(2-((2R,6S)-2,6-Dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol;rel-5-[2-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol;KU0063794(KU63794);KU-0063794(KU 0063794);BENZENEMETHANOL, 5-[2-[(2R,6S)-2,6-DIMETHYL-4-MORPHOLINYL]-4-(4-MORPHOLINYL)PYRIDO[2,3-D]PYRIMIDIN-7 |
| CAS: | 938440-64-3 |
| MF: | C25H31N5O4 |
| MW: | 465.551 |
| EINECS: | |
| Product Categories: | Inhibitors |
| Mol File: | 938440-64-3.mol |
|
|
|
| KU-0063794 Chemical Properties |
| density | 1.248 |
| storage temp. | Store at RT |
| KU-0063794 Usage And Synthesis |
| Biological Activity | Selective inhibitor of mammalian target of rapamycin (mTOR) (IC 50 ~10 nM for mTORC1 and mTORC2 respectively). Displays no activity at PI 3-kinase or 76 other kinases tested. Inhibits activation and hydrophobic motif phosphorylation of Akt, S6K and SGK, but not RSK. Suppresses cell growth and induces G 1 cell cycle arrest in vitro . |
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