RARECHEM AH PB 0251 2156-56-1 C2HCl2NaO2
Sodium dichloroacetate Basic information |
Product Name: | Sodium dichloroacetate |
Synonyms: | dichloroacetate,sodiumsalt;dichloro-aceticacisodiumsalt;dichloroctansodny;Sodiumdichloracetate;NATRIUMDICHLORACETAT;SDA;SODIUM DICHLOROACETATE;DICHLOROACETIC ACID SODIUM SALT |
CAS: | 2156-56-1 |
MF: | C2HCl2NaO2 |
MW: | 150.92 |
EINECS: | 218-461-3 |
Product Categories: | |
Mol File: | 2156-56-1.mol |
Sodium dichloroacetate Chemical Properties |
mp | 198 °C (dec.)(lit.) |
storage temp. | Desiccate at RT |
Water Solubility | soluble in cold water |
Sensitive | Moisture Sensitive |
CAS DataBase Reference | 2156-56-1(CAS DataBase Reference) |
EPA Substance Registry System | Acetic acid, dichloro-, sodium salt(2156-56-1) |
Safety Information |
Hazard Codes | Xi,Xn |
Risk Statements | 36/37/38-40 |
Safety Statements | 26-37/39-36-36/37 |
RIDADR | 2811 |
WGK Germany | 2 |
RTECS | AG9275000 |
MSDS Information |
Provider | Language |
---|---|
Dichloroacetic acid sodium salt | English |
SigmaAldrich | English |
ACROS | English |
ALFA | English |
Sodium dichloroacetate Usage And Synthesis |
Chemical Properties | white powder |
Biological Activity | Inhibitor of mitochondrial pyruvate dehydrogenase kinase (PDK). Shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. Induces mitochondrial-dependent apoptosis and reverses the inhibition/downregulation of K V 1.5 channels in cancer but not normal cells. Decreases tumor growth in vitro and in vivo . |
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