- Min.Order :1 Kilogram
- Purity: 99%
- Payment Terms : L/C,D/A,D/P,T/T,
Keywords
AAG IMMUNOMYCIN 4-hydroxy-3-methoxycyclohexyl
Quick Details
- Appearance:White Solid
- Application:104987-12-4
- PackAge:As required
- ProductionCapacity:100-200|Kilogram|Month
- Storage:?20°C
- Transportation:By air/sea/express
Superiority:
About Certificate
1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)
About Service
1. Quality control, before shipment, free sample for test.
2. Prompt shipment with professional documents
3. Packing as your request, with photo before shipment
4. Mixed containers with different mixed items in one container
About Company
HenNan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.
We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you better with our high - quality products and professional team.
We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.
We welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!
Details:
| Product Name: | Ascomycin |
| Synonyms: | AAG;FK-520;FR-900520;IMMUNOMYCIN;ASCOMYCIN, STREPTOMYCES HYGROSCOPICUS;ASCOMYCIN, STREPTOMYCES HYGROSCOPICUS VAR ASCOMYCETICUS;12,18-tetramethyl-,(3s-(3r*(e(1s*,3s*,4s*)),4s*,19s*,26ar*))--10;8-ethyl-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy |
| CAS: | 104987-12-4 |
| MF: | C43H69NO12 |
| MW: | 792.01 |
| EINECS: | 200-835-2 |
| Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Macrolactams;Antibiotics;Antibiotics A to;Antibiotics A-FAntibiotics;Antibiotics by Application;AntifungalAntibiotics;Antineoplastic and Immunosuppressive AntibioticsAntibiotics;Chemical Structure Class;Inhibits an EnzymeAntibiotics;Mechanism of Action;Spectrum of Activity;antibiotic;Inhibitors |
| Mol File: | 104987-12-4.mol |
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| Ascomycin Chemical Properties |
| mp | 153-157°C |
| storage temp. | −20°C |
| Safety Information |
| Hazard Codes | Xn,F |
| Risk Statements | 20/21/22-36-11 |
| Safety Statements | 36/37-16 |
| WGK Germany | 3 |
| RTECS | KD4185000 |
| F | 10 |
| Ascomycin Usage And Synthesis |
| Chemical Properties | White Solid |
| Usage | A potent immunosuppressive agent and could be used as a potential therapeutic agent for autoimmune diseases |
| Usage | Ascomycin is a macrocyclic lactone closely related to tacrolimus and rapamycin. Ascomycin is isolated from several species of Streptomyces and was first reported in 1988. Ascomycin exhibits limited, potent antifungal activity but has found considerable utility as an immunosuppressant. |
| Usage | Ascomycin is a macrocyclic lactone closely related to tacrolimus and rapamycin. Ascomycin is isolated from several species of Streptomyces and was first reported in 1962. Ascomycin exhibits limited, potent antifungal activity but has found considerable utility as an immunosuppressant. |
| Usage | Everolimus is a semi-synthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group with a silyl-protected hydroxyethyl triflate moiety, followed by addition of an ethylhydroxy moiety to provide greater stability and bioavailability. Like all tacrolimus analogues, everolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing it from interacting with target proteins. Everolimus is extensively cited in the literature with over 2,000 citations. |
| Ascomycin Preparation Products And Raw materials |
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