I-BET151 (GSK121015...

I-BET151 (GSK1210151A)
I-BET151 (GSK1210151A)
I-BET151 (GSK1210151A)

I-BET151 (GSK1210151A)

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100 Kilogram

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  • Min.Order :100 Kilogram
  • Purity: 99%
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I-BET151 (GSK1210151A) 1300031-49-5 C23H21N5O3

Quick Details

  • Appearance:powder
  • Application:1300031-49-5
  • PackAge:Depended
  • ProductionCapacity:300|Kilogram|Month
  • Storage:Store in dry, dark and ventilated place
  • Transportation:by air or by sea

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I-BET151 (GSK1210151A) Basic information
Product Name: I-BET151 (GSK1210151A)
Synonyms: 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one;GSK 1210151A;I-BET 151;I-BET 151/GSK 1210151A;GSK1210151A (I-BET151);7-(3,5-diMethylisoxazol-4-yl)-8-Methoxy-1-((R)-1-(pyridin-2-yl)ethyl)-1H-iMidazo[4,5-c]quinolin-2(3H)-one;7-(3,5-Dimethylisoxazol-4-yl)-8-methoxy-1-((R)-1-(pyridin-2-yl)ethyl)-1H-imidazo[4,5-c]quinolin-2;7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one I-BET151(GSK1210151A)
CAS: 1300031-49-5
MF: C23H21N5O3
MW: 415.44454
EINECS:  
Product Categories: Inhibitors
Mol File: 1300031-49-5.mol
I-BET151 (GSK1210151A) Structure
 
I-BET151 (GSK1210151A) Chemical Properties
density  1.314
storage temp.  2-8°C
 
Safety Information
Hazard Codes  T
Risk Statements  25
Safety Statements  45
MSDS Information
 
 
I-BET151 (GSK1210151A) Usage And Synthesis
Chemical Properties Off-White Solid
Usage I-BET 151 is part of a novel series of quinoline isoxazole BET family bromodomain inhibitors, a family of four proteins that selectively bind to aceylated lysine residues in histone. I-BET 151 play ke y roles in many cellular processes, including anti-inflammatory gene expression, mitosis, and viral/host interaction by controlling the conformation of histone acetylation -dependent chromatin complex es. Studies have shown that I-BET 151 increased ApoA1 expression within the nanomolar range in human hepatic cell line HepG2. The upregulation by I-BET 151 suggested potential anti-inflammatory activi ties upon administration.

 

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