Domperidone

Domperidone

Domperidone

Min.Order / FOB Price:Get Latest Price

10 Gram

Negotiable

  • Min.Order :10 Gram
  • Purity: 99%+
  • Payment Terms : L/C,D/A,D/P,T/T,

Keywords

57808-66-9 Domperidone Motilium

Quick Details

  • Appearance:white or almost white powder
  • Application:Peripheral dopamine receptor antagonist; antiemetic
  • PackAge:1kg/package, 25kg/bag, 25kg/drum
  • ProductionCapacity:30|Kilogram|Month
  • Storage:protected from light
  • Transportation:By air, by courier, by sea

Superiority:

XI'AN VEDA CHEMICAL CO.,LTD(VEDACHEM), is specializes in APIs and Intermediates.

Domperidone is one of the main products in VEDACHEM.

Domperidone (INN, USAN, BAN, JAN) (brand name Motilium, many

others) is a drug developed by Janssen Pharmaceutica that acts as

a peripherallyselective antagonist of the dopamine D2 and D3 receptors.

It is administered orally, rectally, or intravenously. Domperidone is used

to relievenausea and vomiting; to increase the transit of food through

the stomach (that is, as a prokinetic agent via 

increasing gastrointestinal peristalsis); and to promote lactation (breast

milk production) by release of prolactin. It is also used in scientific

research to study the biological function of dopamine, an

important neurotransmitter and hormone, in the body.

Domperidone is available in the form of tablets, orally disintegrating

tablets (based on Zydis technology), suspension and suppositories.

 

We can supply Domperidone  in sample grade or medicine grade.

Please  contact us for detailed information, such as COA/MSDS/MOA, etc.

Details:

product Name

Domperidone

Synonyms

alpha-[2-(diisopropylamino) ethyl]-alpha-phenyl-2-pyridineacetamide; Motilium

Molecular Formula

C22H24ClN5O2

Molecular Weight

425.92

InChI

InChI=1/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30)

CAS Registry Number

57808-66-9

EINECS

260-968-7

Molecular Structure

Hazard Symbols

Xn:Harmful;

Risk Codes

R62:;
R63:;

Safety Description

S26:;
S36:;

 

Appearance

 

White or almost white powder

Solubility

Practically insoluble in water, soluble in dimethylformamide, slightly soluble in ethanol (96 per cent) and in methanol.

Identification

Melting point

244℃ to 248℃

IR

Correspond with CRS

Thin-layer chromatography

Gives reaction of non-nitrogen substituted barbiturates

Appearance of solution

Clear and not more intensely coloured than reference solution Y6

Related substances

Impurity A:

Not more than 0.25%

Impurity B:

Not more than 0.25%

Impurity C:

Not more than 0.25%

Impurity D:

Not more than 0.25%

Impurity E:

Not more than 0.25%

Impurity F:

Not more than 0.25%

Total impurities

Not more than 0.5%

Disregard limit

Not more than 0.05%

Heavy metals

Maximum 20ppm

Loss on drying

Maximum 0.5%

Sulphated ash

Maximum 0.1%

Storage

Protected from light

 

Domperidone API

Domperidone Drug

Domperidone  function

 

 

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