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factory lower price 	520-36-5
factory lower price 	520-36-5
factory lower price 	520-36-5

factory lower price 520-36-5

Min.Order / FOB Price:Get Latest Price

100 Kilogram

Negotiable

  • Min.Order :100 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

Apigenin 520-36-5 C15H10O5

Quick Details

  • Appearance:powder
  • Application: 520-36-5
  • PackAge:Depended
  • ProductionCapacity:300|Kilogram|Month
  • Storage:Refrigerator
  • Transportation:by air or by sea

Superiority:

Apigenin Basic information
Product Name: Apigenin
Synonyms: APIGENIN;CHAMOMILE;4',5,7-TRIHYDROXYFLAVONE;4,5,7-TRIHYDROXYFLAVONE;4',5,7-TRIHYROXYFLAVONE;5,7,4'-TRIHYDROXYFLAVONE;5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)-4H-1-BENZOPYRAN-4-ONE;7,4',5-TRIHYDROXYFLAVONE
CAS: 520-36-5
MF: C15H10O5
MW: 270.24
EINECS: 208-292-3
Product Categories: Tri-substituted Flavones;Biochemistry;Flavonoids;Natural Plant Extract;Inhibitors;Protein Kinase;Signalling;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;natural product;Plant extract
Mol File: 520-36-5.mol
Apigenin Structure
 
Apigenin Chemical Properties
mp  >300 °C(lit.)
storage temp.  −20°C
solubility  DMSO: 27 mg/mL
form  powder
color  yellow
Merck  14,730
BRN  262620
CAS DataBase Reference 520-36-5(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  LK9276000
10
HS Code  29329985
Hazardous Substances Data 520-36-5(Hazardous Substances Data)
MSDS Information
Provider Language
SigmaAldrich English
ALFA English
 
Apigenin Usage And Synthesis
Chemical Properties Pale Yellow Crystalline Solid
Usage antispasmodic, antineoplastic, topoisomerase I inhibitor
Usage Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tum or cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap juntion intracellular communication in liver cells.
Biological Activity Protein kinase inhibitor. Suppresses tumor-promoting effects of TPA and exhibits antiproliferative activity in human breast cancer cells (IC 50 values are 59.44 and 31.15 μ M at 24 and 72 hrs respectively). Activates both the intrinsic and extrinsic apoptotic pathways and displays anti-inflammatory, hypotensive, antispasmodic and antioxidant properties in vivo .
 
 

 

 

 

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