Betulinic acid 472-15-1 C30H48O3
Betulinic acid Basic information |
Product Name: | Betulinic acid |
Synonyms: | 3BETA-HYDROXY-20(29)-LUPENE-28-OIC ACID;3BETA-HYDROXY-20(29)-LUPAENE-28-OIC ACID;3B-HYDROXY-20(29)-LUPENE-28-OIC ACID;3-B-HYDROXY-LUPA-20(30)-ENE 28-OIC ACID;BETULINIC ACID;BETULIC ACID;MAIRIN;LUP-20(29)-EN-28-OIC ACID, 3-HYDROXY-, (3B)- |
CAS: | 472-15-1 |
MF: | C30H48O3 |
MW: | 456.7 |
EINECS: | 207-448-8 |
Product Categories: | Pentacyclic Triterpenes;Tri-Terpenoids;sy;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Antineoplastic;natural product;Inhibitors;Triterpenoids |
Mol File: | 472-15-1.mol |
Betulinic acid Chemical Properties |
mp | 295-298 °C (dec.)(lit.) |
refractive index | 7.8 ° (C=0.9, Pyridine) |
storage temp. | Store at +4°C |
Merck | 1190 |
CAS DataBase Reference | 472-15-1(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xi |
WGK Germany | 3 |
HS Code | 29181985 |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
Betulinic acid Usage And Synthesis |
Chemical Properties | colorless Needles |
Usage | antineoplastic |
Usage | Betulinic Acid is a natural pentacyclic triterpenoid. Betulinic Acid displays anti-inflammatory and anti-HIV activity. Betulinic Acid selectively induces apoptosis in tumor cells by directly activati ng the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic Acid also exhibits TGR5 agonist activity |
Biological Activity | Natural triterpenoid that displays anti-HIV and antitumor activity. Induces the production of reactive oxygen species (ROS) and activates NF- κ B. Exhibits TRG5 agonist activity (EC 50 = 1.04 μ M). |
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