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Buy 21679-14-1 Fludarabine 99% purity Supply 21679-14-1 with stable production Hot sale ! 21679-14-1 for pharmaceutical intermediates
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PRODUCT INFORMATION :
Fludarabine Basic information |
Product Name: | Fludarabine |
Synonyms: | 2-Fluoroadeninearabinoside;9-beta-d-arabinofuranosyl-2-fluoro-9h-purin-6-amin;9-beta-d-arabinofuranosyl-2-fluoro-adenin;f-ara-a;6-AMINO-9 BETA-D-ARABINOFURANOSYLFLUOROPURINE;9-bata-d-arabinofuranosyl-2-fluoroadenine;9-BETA-D-ARABINOFURANOSYL-2-FLUORO-9H-PURIN-6-AMINE;9-BETA-D-ARABINOFURANOSYL-2-FLUOROADENINE |
CAS: | 21679-14-1 |
MF: | C10H12FN5O4 |
MW: | 285.23 |
EINECS: | 244-525-5 |
Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;API;F-ara-A, NSC 118218;Anti-cancer&immunity;Inhibitors |
Mol File: | 21679-14-1.mol |
Fludarabine Chemical Properties |
mp | 265-268°C |
storage temp. | 2-8°C |
solubility | DMF: 20 mg/mL, clear, faintly yellow |
Merck | 13,4152 |
CAS DataBase Reference | 21679-14-1(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xn |
Risk Statements | 23/24/25-36/37/38-39/23/24/25-39-22 |
Safety Statements | 26-36/37-45 |
WGK Germany | 3 |
RTECS | AU6207000 |
F | 10 |
Hazardous Substances Data | 21679-14-1(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
9-bata-D-Arabinofuranosyl-2-fluoroadenine | English |
SigmaAldrich | English |
Fludarabine Usage And Synthesis |
Chemical Properties | White Solid |
Usage | Used as an antineoplastic |
Usage | A STAT-1 activation inhibitor and a DNA synthesis inhibitor. |
Usage | phosphate as antineoplastic;inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase |
Usage | Irreversible muscarinic agonist |
Usage | DNA synthesis and methylation inhibitor;A cell permeable agent that interferes with DNA synthesis and repair; also inhibits RNA transcription |
Biological Activity | Purine analog that inhibits DNA synthesis. Exhibits antiproliferative activity (IC 50 = 1.54 μ M in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP and survivin expression. Displays anticancer activity against hematological malignancies in vivo . |
Fludarabine Preparation Products And Raw materials |
Raw materials | Acetic anhydride-->Fluoroboric acid-->Boron trichloride -->2,4,5,6-TETRAAMINOPYRIMIDINE-->2,6-Diaminopurine-->DIACETAMIDE |
1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.
2. Quality assurance: we have a first-class testing equipment and testing personnel, in strict accordance with ISO and cGMP standards, ensure that the quality of the shipment.
3.Ultra-low prices, we follow the meager profit but high turnover principle to win more customers, to provide you with quality and cheap products.
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5. Customer groups: our clients throughout the world more than 30 countries, high quality products, low price, best service to win the customer's consistent high praise.
If you demand the product, you are welcome to contact us at any time, we guarantee that you seriously every inquiry, give you the fastest reply and the best service.
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