(R)-1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-phenanthro(1,2-b)furan-10,11-dione 35825-57-1 C19H20O3
(R)-1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-phenanthro(1,2-b)furan-10,11-dione Basic information |
Product Name: | (R)-1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-phenanthro(1,2-b)furan-10,11-dione |
Synonyms: | CRYPTOTANSHINONE;(r)-1,2,6,7,8,9-hexahydro-1,6,6-trimethyl-phenanthro(1,2-b)furan-10,11-dione;TANSHINONE, CRYPTO;98% BY HPLC;CRYPTOTANSHINONE >;TANSHINONE, CRYPTO(P);hexahydro-1,6,6-trimethyl-,(R)-;Phenanthro[1,2-b]furan-10,11-dione,1,2,6,7,8,9- |
CAS: | 35825-57-1 |
MF: | C19H20O3 |
MW: | 296.36 |
EINECS: | |
Product Categories: | Anthraquinones, Hydroquinones and Quinones;The group of Danshen;Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors |
Mol File: | 35825-57-1.mol |
(R)-1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-phenanthro(1,2-b)furan-10,11-dione Chemical Properties |
storage temp. | Store at RT |
CAS DataBase Reference | 35825-57-1(CAS DataBase Reference) |
(R)-1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-phenanthro(1,2-b)furan-10,11-dione Usage And Synthesis |
Chemical Properties | Orange powder |
Usage | inhibits angiogenesis |
Biological Activity | Major tanshinone isolated from Salvia miltiorrhiza that exhibits multiple activities. Exhibits antitumor activity via inhibition STAT3 activity (IC 50 = 4.6 μ ). Displays antibacterial and anti-inflammatory activity and acts as an antidiabetes and antiobesity agent via activation of AMP-activated protein kinase (AMPK). Also improves cognitive impairment in Alzheimer's disease transgenic mice by inhibition of acetylcholinesterase (IC 50 = 4.09 μ ) and reduction in A β peptide generation. |
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