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Molecular Weight: 130.077223 [g/mol]
Molecular Formula: C4H3FN2O2
XLogP3: -0.9
H-Bond Donor: 2
H-Bond Acceptor: 3
EINECS: 200-085-6
Melting Point: 282-286 °C (dec.)(lit.)
Surface Tension: 46.1 dyne/cm
Density: 1.53 g/cm3
Flash Point: 196.5 °C
Enthalpy of Vaporization: 67.78 kJ/mol
Boiling Point: 401.4 °C at 760 mmHg
Vapour Pressure: 5.13E-07 mmHg at 25°C
Water Solubility: 12.2 g/L 20 °C
Sensitive: Air Sensitive
Stability: Stable. Light sensitive. Combustible. Incompatible with strong oxidizing agents, strong bases.
Function:
1. It is used for biochemical studies and antitumor drugs.
2. It is the anti tumor drug, also used for synthesis of flucytosine. 5- fluorouracil can be used in the study of rice in the biochemical studies, ear differentiation, genetic metabolic measurement, plant growth development research.
3. It is used for the digestive system cancer, head and neck cancer, gynecological cancer, lung cancer, liver cancer, treatment of bladder cancer and skin cancer.
4. Antimetabolite antitumor drugs.
5. Anti tumor drugs. There is a certain effect on a variety of tumors such as digestive tract cancer, breast cancer, ovarian cancer, chorionic epithelial cancer, cervical cancer, hepatocellular carcinoma, bladder cancer, skin cancer (topical), leukoplakia (topical) etc. Adverse reactions mainly are bone marrow transplantation, digestive tract reaction, serious person can have diarrhea, local injection site phlebitis, a few of which have nervous system reactions such as cerebellar degeneration and ataxia. The course of medication should strictly check the blood.
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CAS NO. |
51-21-8 |
Product Name |
5-Fluorouracil |
Synonyms
|
Ro-2-9757; Phtoruracil; Ulup; 2,4(1H,3H)-Pyrimidinedione,5-fluoro-; Phthoruracil; Uracil, 5-fluoro-; 5-Fluoro-2,4(1H, 3H)-pyrimidinedione; 2,4 (1H, 3H)-Pyrimidinedione, 5-fluoro-; 5-Fluoro-2,4(1H,3H)-pyrimidinedione; Fluoroplex; 5-Fluoracyl; Efudex; Effluderm (free base); 5-Ftouracyl;
5-Fluoropyrimidine-2,4-dione; |
Structure |
|
Purity |
99% |
Molecular Formula |
C4H3FN2O2 |
Molecular Weight |
130.0772 |
Flash Point |
196.5 °C |
Refractive index |
1.542 |
InChI |
InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9) |
Boiling Point |
401.4 °C at 760 mmHg |
Density |
1.53 g/cm3 |
Melting Point |
278-286℃ |
Storage Temperature |
|
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