CASTANOSPERMINE 79831-76-8 C8H15NO4
CASTANOSPERMINE Basic information |
Product Name: | CASTANOSPERMINE |
Synonyms: | 1,6,7,8-indolizinetetrol,octahydro-,(1s-(1-alpha,6-beta,7-alpha,8-beta,8a-bet;7,8-indolizinetetrol,octahydro-,(1s,6s,7r,8r,8ar)-6;octahydro-1,6,7,8-indolizinetetrol(1s-(1-alpha,6-beta,7-alpha,8-beta,8a-beta;CASTANOSPERMINE;CASTANOSPERMINE, CASTANOSPERMUM AUSTRALE;1,6,7,8-TETRAHYDROXYOCTAHYDROINDOLIZINE;[1S-(1A,6B,7A,8B,8A-BETA)]-OCTAHYDRO-1,6,7,8-INDOLIZINETETROL;(1S,6S,7R,8AR)-TETRAHYDROXYOCTAHYDROINDOLIZINE |
CAS: | 79831-76-8 |
MF: | C8H15NO4 |
MW: | 189.21 |
EINECS: | |
Product Categories: | Alkaloids;All Inhibitors;Glycosidase Inhibitors;Inhibitors;Miscellaneous Enzyme;inhibitor |
Mol File: | 79831-76-8.mol |
CASTANOSPERMINE Chemical Properties |
mp | 213-217 °C(lit.) |
storage temp. | 2-8°C |
solubility | 1 M HCl: 20 mg/mL, clear, very faintly yellow |
Merck | 13,1906 |
CAS DataBase Reference | 79831-76-8(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xn,Xi |
Risk Statements | 20/21/22-36/37/38 |
Safety Statements | 26-36 |
WGK Germany | 3 |
F | 10-21 |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
CASTANOSPERMINE Usage And Synthesis |
Chemical Properties | White Crystalline Solid |
Usage | Castanospermine is a plant alkaloid shown to be a potent inhibitor of lysosomal a-or beta- glucosidase. It also inhibits mammalian glucosidase 1 and beta-mannosidase from sweet almonds and fungal beta-xylosidase. |
Usage | a-L-fucosidases inhibitor |
Biological Activity | Potent inhibitor of α - and β -glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids). Inhibits HIV syncytium formation and replication. |
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