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qualified of 5-Fluorouracil pharmaceutical intermediate 51-21-8  china

qualified of 5-Fluorouracil pharmaceutical intermediate 51-21-8 china

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1 Kilogram

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  • Min.Order :1 Kilogram
  • Purity: 99.0%min
  • Payment Terms : T/T

Keywords

pharmaceutical intermediate 51-21-8 qualified of 5-Fluorouracil 5-Fluorouracil china

Quick Details

  • Appearance:White powder
  • Application:Anti tumor drug. For a variety of cancers such as gastrointestinal cancer, breast cancer, ovarian cancer, chorionic epithelial cancer, cervical cancer, liver cancer, bladder cancer, skin cancer (topic
  • PackAge:25kg firber drum
  • ProductionCapacity:5|Metric Ton|Day
  • Storage:dry and cool place
  • Transportation:by sea or air

Superiority:

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Over the years, the company adhere to market-oriented, technology and development, quality of life for the purpose. Strengthening enterprise management, has a high quality, the ability to develop strong and rich experience in the production of professional and technical teams. Production of advanced technology, sophisticated equipment, means of improving detection.

Our products are exported to the United States, European Union, Southeast Asia and other countries and regions. Users both here and abroad and has established long-term and stable supplier relations, occupies a stable market share and to maintain sustained growth. And with domestic and foreign universities, research institutes and some well-known companies have extensive cooperation and close ties.

We follow the "quality and integrity" business philosophy, For Chinese and foreign customers to provide quality products and services in order to do long-term win-win business, and seek common development. We sincerely welcome friends from all over the world to exchange and cooperation!

 

Details:

Specifications

5-Fluorouracil have high quality and competitive prices
51-21-8 in stock
We are factory and manufacturer

CAS NO.

51-21-8

Product Name

5-Fluorouracil

Synonyms

 

Ro-2-9757;

Phtoruracil; Ulup;

2,4(1H,3H)-Pyrimidinedione,5-fluoro-;

Phthoruracil;

Uracil, 5-fluoro-;

5-Fluoro-2,4(1H, 3H)-pyrimidinedione;

2,4 (1H, 3H)-Pyrimidinedione, 5-fluoro-;

5-Fluoro-2,4(1H,3H)-pyrimidinedione; Fluoroplex;

5-Fluoracyl; Efudex;

Effluderm (free base);

5-Ftouracyl;

 

5-Fluoropyrimidine-2,4-dione;

Structure

5-Fluorouracil CAS NO.:51-21-8

Purity

99%

Molecular Formula

C4H3FN2O2

Molecular Weight

 130.0772

Flash Point

196.5 °C

Refractive index

1.542

InChI

InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)

Boiling Point

401.4 °C at 760 mmHg

Density

1.53 g/cm3

Melting Point

278-286℃

Storage Temperature

Store at 0-5℃

Introduction: 

Fluorouracil or 5-FU (trademarked as Adrucil(IV), Carac (topical), Efudex and Efudix (topical)) is a drug that is a pyrimidine analog which is used in the treatment of cancer. It is a suicide inhibitor and works through irreversible inhibition ofthymidylate synthase. It belongs to the family of drugs called the antimetabolites.

It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system.

5-Fluorouracil (5-FU) is widely used in the treatment of cancer. Over the past 20 years, increased understanding of the mechanism of action of 5-FU has led to the development of strategies that increase its anticancer activity. Despite these advances, drug resistance remains a significant limitation to the clinical use of 5-FU. Emerging technologies, such as DNA microarray profiling, have the potential to identify novel genes that are involved in mediating resistance to 5-FU. Such target genes might prove to be therapeutically valuable as new targets for chemotherapy, or as predictive biomarkers of response to 5-FU-based chemotherapy.

 

Usage:

Fluorouracil (CAS NO.51-21-8) can be used in against cancer for about 40 years, acts in several ways, but principally as a thymidylate synthase inhibitor. It can be used in colorectal cancer and pancreatic cancer,also it can be used for treating actinic (solar) keratoses and some types of basal cell carcinomas of the skin.

Fluorouracil has been given systemically for analbreastcolorectal,oesophagealstomachpancreatic and skin cancers (especially head and neck cancers). It has also been given topically for actinic keratosesskin cancers and Bowen's disease.

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