ABT-199 Intermediates CAS No.98549-88-3 Venetoclax intermediate

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Vemurafenib & intermediate

No.

Product Name

CAS No.

1.

Vemurafenib, PLX4032

1029872-54-5

2.

5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridine

918516-27-5

3.

2,6-difluoro-3-(propylsulfonamido)benzoic acid

1103234-56-5

4.

PLX-4720,   N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide

918505-84-7

5.

N-(3-(5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide

918504-27-5

Indacaterol& intermediate

1.

Indacaterol

312753-06-3

2.

(R)-8-(benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one

173140-90-4

3.

8-(benzyloxy)-5-(2-bromoacetyl)quinolin-2(1H)-one

100331-89-3

4.

5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride

312753-53-0

Lurasidone& intermediate

1.

Bicyclo[2.2.1]hep-tane-2,3-exo- dicarboximide

14805-29-9

2.

(1R,2R)-1,2-Cyclohexanedimethanol

65376-05-8

3.

(1R,2R)-Trans-1,2 bis (methan sulfonyl-oxymethyl) Cyclohexane

186204-35-3

Cabozantinib& Tivozanib intermediate

1.          

4-chloro-6,7-dimethoxyquinoline

35654-56-9

2.          

4-((6,7-dimethoxyquinolin-4-yl)oxy)aniline

190728-25-7

3.          

1-((4-fluorophenyl)carbamoyl)cyclopropanecarboxylic acid

849217-48-7

4.          

Phenyl(2-chloro-4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)carbamate

Ivabradine & intermediates

1.

(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride

866783-13-3

2.

3-(3-Chloropropyl)-7,8-dimethoxy-1H-3-benzazepin-2(3H)-one

85175-59-3

3.

7,8-dimethoxy-3-(3-iodopropyl)-1,3-dihydro-2H-3-benzaze pin-2-one

148870-57-9

4.

8-Demethyl Ivabradine

304464-97-9

Edoxaban& intermediates

1.

(1S)-cyclohex-3-ene-1-carboxylic acid

5708-19-0

2.

(1R)-cyclohex-3-ene-1-carboxylic acid

5709-98-9

3.

Ethyl(1S,3R,4R)-3-((tert-butoxycarbonyl)amino)-4-hydroxycyclohexane-1-carboxylate

365997-33-7

4.

Tert-butyl((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate

1210348-34-7

5.

5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxylic acid

720720-96-7

6.

N-(5-chloro-pyridin-2-yl)-oxalamic acid ethyl ester

349125-08-2

Ticagrelor inter. Isomers

1.

(1S,2R)-2-(3,4-difluorophenyl)cyclopropan-1-amine

 1345413-20-8

2.

(1R,2R)-2-(3,4-difluorophenyl)cyclopropan-1-amine

3.

(1S,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine

4.

2-(((3aS,4R,6S,6aR)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

Other API products

1.          

Tigecycline 99.9% GMP or 99.8%

220620-09-7

2.          

Abiraterone acetate 99.5%

154229-18-2

3.          

Daunorubicin Hydrochloride 98.9%

23541-50-6

4.          

Galanthamine hydrobromide 99.7%

1953-04-4

5.          

Epalrestat, 99.5%

82159-09-9

6.          

Ceritinib

1032900-25-6

7.          

Oxiracetam 99.7%

62613-82-5

Fine chemical product

1.          

N-Benzylhydroxylamine hydrochloride

29601-98-7

2.          

2-aminoindan hydrochloride

2338-18-3

3.          

D(-)-Ribose

50-69-1

4.          

4-hexylbenzoic acid

21643-38-9

5.          

4-cyanophenyl 4-hexylbenzoate

50793-85-6

6.          

2-chloro-5-(methoxycarbonyl)benzoic

651058-97-8

IN DEVELOPMENT PROCESS for the intermediates of ABT-199, Venetoclax

1.          

ABT-199, Venetoclax

1257044-40-8

2.          

4-fluoro-3-nitrobenzenesulfonamide

406233-31-6

3.          

3-Nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide

1228779-96-1

4.          

1H-Pyrrolo[2,3-b]pyridin-5-ol

98549-88-3

5.          

Ethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate

1630101-74-4

6.          

Methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate

1235865-75-4

7.          

3,3-Dimethylcyclohexanone

2979-19-3

8.          

(4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methanol

1228837-05-5

9.          

1-[[2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-enyl]methyl]piperazine

1228780-72-0

10.      

Tert-butyl4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine-1-carboxylate

1228780-71-9

11.      

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid

1235865-77-6

Cinchona Alkaloids Products List

Quinine& derivatives

No.

Product Name

CAS No.

1.

Quinine, (R)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol

130-95-0

2.

9-Amino-(9-deoxy)epi-quinine trihydrochloride

168960-95-0

Dihydroquinine& derivatives

1.

Dihydroquinine (R)-((1S,2S,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methanol

522-66-7

2.

9-Amino-(9-deoxy)epi-dihydroquinine trihydrochloride

931098-91-8

3

(DHQ)2PYR;Hydroquinine 2,5-diphenyl-4,6-pyrimidinediyl Diether

149820-65-5 

Quinidine & derivatives

1.

Quinidine;(S)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methanol

56-54-2

2.

9-Amino-(9-deoxy)epi- quinidine trihydrochloride

1391506-12-9

Dihydroquinidine& derivatives

1.

Dihydroquinidine;(S)-((1S,2R,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methanol

1435-55-8

2.

9-Amino-(9-deoxy)epi- dihydroquinidinetrihydrochloride

931098-92-9

3

(DHQD)2PYR; Hydroquinidine-2,5-diphenyl-4,6-pyrimidinediyl Diether

149725-81-5

Cinchonine& derivatives

1.

Cinchonine ;(S)-quinolin-4-yl((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methanol

118-10-5

2.

9-Amino-(9-deoxy)epi-Cinchonine trihydrochloride

168960-96-1

Dihydrocinchonine& derivatives

1.

Dihydrocinchonine ;(S)-((1S,2R,4S,5R)-5-ethylquinuclidin-2-yl)(quinolin-4-yl)methanol

485-65-4

2.

9-Amino-(9-deoxy)epi- Dihydrocinchonine trihydrochloride

354532-49-3

Cinchonidine& derivatives

1.

Cinchonidine;(R)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol

485-71-2

2.

9-Amino-(9-deoxy)epi- Cinchonidine trihydrochloride

850409-61-9

Dihydrocinchonidine & derivatives

1.

Dihydrocinchonidine;

(R)-((1S,2S,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methanol

485-64-3

2.

9-Amino-(9-deoxy)epi-Dihydrocinchonidinetrihydrochloride