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633-65-8
Berberine hydrochloride Basic information |
Product Name: | Berberine hydrochloride |
Synonyms: | TIMTEC-BB SBB006488;NATURAL YELLOW 18 CHLORIDE;NATURAL YELLOW 18;UMBELLATINE;5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE;BERBERINE HCL;BERBERINE HYDROCHLORIDE;BERBERIN HCL |
CAS: | 633-65-8 |
MF: | C20H18ClNO4 |
MW: | 371.81 |
EINECS: | 211-195-9 |
Product Categories: | Natural Plant Extract;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Plant extracts;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract |
Mol File: | 633-65-8.mol |
Berberine hydrochloride Chemical Properties |
mp | 204-206 °C (dec.) |
Water Solubility | SOLUBLE IN COLD WATER |
EPA Substance Registry System | Benzo[g]-1,3-benzodioxolo[ 5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride(633-65-8) |
Safety Information |
Hazard Codes | Xn |
Risk Statements | 20/21/22-36/37/38 |
Safety Statements | 24/25-36-26 |
RIDADR | 1544 |
WGK Germany | 2 |
RTECS | DR9866400 |
F | 3-10 |
HazardClass | 6.1(b) |
PackingGroup | III |
MSDS Information |
Provider | Language |
---|---|
Natural Yellow 18 | English |
SigmaAldrich | English |
Berberine hydrochloride Usage And Synthesis |
Chemical Properties | yellow crystalline powder |
Usage | antiarrhythmic, alpha2 agonist, anticonvulsant, antiinflammatory, antibacterial, antifungal, antitrypanosomal, antineoplastic, immunostimulant |
Usage | An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Al so inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation o f chemotherapeutic drugs. |
Usage | An ingredient in some commercial eyewash products. |
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