6132-4-3 C6H9Na3O9 Trisodium citrate dihydrate

6132-4-3 C6H9Na3O9 Trisodium citrate dihydrate

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5 Gram	Negotiable

5 Gram

Negotiable

Min.Order :5 Gram
Purity: 98%
Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

6132-4-3 C6H9Na3O9 Trisodium citrate dihydrate 6132-4-3 C6H9Na3O9

Quick Details

Appearance:white powder
Application:An anticoagulant also used as a biological buffer
PackAge:Woven bag
ProductionCapacity:1|Kilogram|Day
Storage:Normal temperature
Transportation:Ocean shipping Express delivery

Superiority:

Trisodium citrate dihydrate Basic information

General description Excellent performance Reference quality standards Effect and application The maximum allowed amount of food additives and maximal permitted residue limits Chemical Properties Application Production methods

Product Name:	Trisodium citrate dihydrate
Synonyms:	1,2,3-Propanetricarboxylicacid,2-hydroxy-,trisodiumsalt,dihydrate;ANTI-BABOON IGM, BIOTIN;BETA-HYDROXY-TRICARBOXYLIC ACID MONOHYDRATE;HYDROXYTRICARBALLYLIC ACID MONOHYDRATE;CITRIC ACID NA3-SALT 2H2O;CITRIC ACID H2O;CITRIC ACID TRISODIUM SALT DIHYDRATE;CITRIC ACID, 3NA, DIHYDRATE
CAS:	6132-04-3
MF:	C6H9Na3O9
MW:	294.1
EINECS:	201-069-1
Product Categories:	INORGANIC & ORGANIC CHEMICALS;FOOD ADDITIVES;Food and Feed Additive;ACS Grade;Biochemicals and Reagents;Biological Buffers;Buffers A to Z;Building Blocks;Carbonyl Compounds;Carboxylic Acid Salts;Chelators;Chemical Synthesis;Essential Chemicals;Inorganic Salts;Organic Building Blocks;Research Essentials;Solutions and Reagents;Food additive and acidulant
Mol File:	6132-04-3.mol

Trisodium citrate dihydrate Chemical Properties

mp	>300 °C(lit.)
density	1.76
FEMA	3026
Fp	173.9 °C
storage temp.	Store at RT.
solubility	H₂O: 100 mg/mL
form	powder
color	white
Water Solubility	720 g/L (25 ºC)
Merck	14,8602
BRN	6104939
Stability:	Stable. Incompatible with bases, reducing agents, oxidizing agents.
CAS DataBase Reference	6132-04-3(CAS DataBase Reference)
EPA Substance Registry System	1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate(6132-04-3)

Safety Information

Hazard Codes	Xi
Risk Statements	37/38-41-36/37/38
Safety Statements	26-36/37/39-24/25-36
WGK Germany	1
RTECS	GE7810000

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

Trisodium citrate dihydrate Usage And Synthesis

General description	Sodium citrate, (molecular formula: Na3C6H5O7 • 2H2O) has molecular weight of 294.1, is a colorless crystal or white crystalline powder product; it is odorless, salty taste, and cool. It will lose its crystal water at 150 °C and will be decomposed at even higher temperature. It also has slight deliquescence in wet air and has weathering property upon hot air. It is soluble in water and glycerol, but insoluble in alcohol and some other organic solvents. Sodium citrate has no toxic effect, and has pH adjusting capability as well as having a good stability, and therefore can be used in the food industry. Sodium citrate has the greatest demand when being used as a food additive; As food additives, it is mainly used as flavoring agents, buffers, emulsifiers, bulking agents, stabilizers and preservatives; in addition, combination between sodium citrate and citric acid can be used in a variety of jams, jelly, juice, drinks, cold drinks, dairy products and pastries gelling agents, flavoring agents and nutritional supplements.
Excellent performance	Sodium citrate is currently the most important citrate. It is produced by two steps: first starch food is fermented to generate citric acid; secondly, citric acid is neutralized by alkali to generate the final products. Sodium citrate has the following excellent performance: (1) Safe and nontoxic properties; Since the basic raw material for the preparation of sodium citrate mainly comes from the food, it is absolutely safe and reliable without causing harm to human health. The United Nations Food and Agriculture and the World Health Organization has no restriction in its daily intake, which means that this product can be considered as non-toxic food. (2) It is biodegradable. After subjecting to the dilution of a large amount of water, sodium citrate is partially converted into citrate, which coexists with sodium citrate in the same system. Citrate is easy to subject to biological degradation at water by the action of oxygen, heat, light, bacteria and microbes. Its decomposition pathways are generally going through aconitic acid, itaconic acid, citraconic acid anhydride to be further converted to carbon dioxide and water. (3) The ability of forming complex with metal ions. Sodium citrate has a good capability of forming complex with some metal ions such as Ca2+, Mg2+; for other ions such as Fe2+, it also has a good complex-forming ability. (4) Excellent solubility, and the solubility increases with increasing temperature of water. (5) It has a good capability for pH adjustment and a good buffering property. Sodium citrate is a weak acid-strong alkali salt; When combined with citrate, they can form a pH buffer with strong compatibility; therefore, this is very useful for some cases in which it is not suitable to have large change of pH value. In addition, sodium citrate also has excellent retardation performance and stability. The above information is edited by the chemicalbook of Dai xiongfeng.
Reference quality standards	British Pharmacopoeia BP98 Edition Quality Item Technical Index Content 99.0-101.0% PH Meet the rule Heavy Metal (PB) ≤ 0.001% Arsenic ≤ 0.0001% Ferric ≤ 0.001% Oxalate ≤ 0.03% Sulfate ≤ 0.015% Readily carbonizable substance Meet the rule Chloride ≤ 0.005% Water 11.0-13.0% Appearance of the solution clear and transparent solution, colorless Pyrogen consistent with the test
Effect and application	During the process of clinically taking fresh blood, adding some amount of sterile sodium citrate can play a role in prevent blood clotting; this is exactly taking advantage of the features that calcium citrate can form soluble complexes with calcium ion; In the field of medicine, it is used for the in vitro anti- clotting drugs and anticoagulants drugs, phlegm drugs, and diuretics drugs during blood transfusions; it can also used for cyanide-free electroplating industry; also used as developer for photographic industry. It can be used as flavoring agents, buffering materials, emulsifiers, and stabilizer in the food industry. Moreover, it is also widely used in chemical, metallurgical industry, the absorption of sulfur dioxide exhaust with the absorption rate of 99% and regenerate liquid sulfur dioxide citrate for recycle application. Sodium citrate has a good water solubility and a excellent cheating capability with Ca2 +, Mg2 + and other metal ions; it is biodegradable and has a strong dispersing ability and anti-redeposition ability; Daily-applied chemical detergents use it as alternative to trimer sodium phosphate for production of non-phosphorus detergent and phosphate-free liquid detergent. Adding a certain amount sodium citrate to the detergent can significantly increase the cleaning ability of detergent cleaning. The large scale of application of sodium tripolyphosphate as a builder in detergents is an important discovery in synthetic detergent industry. It is non-toxic without environmental pollution; it can also be acted as a buffer for the production of cosmetics.
The maximum allowed amount of food additives and maximal permitted residue limits
Chemical Properties	It is colorless crystals or white crystalline powder, and is odorless, cool and salty. It has no melting point with a relative density of 1.857. It is stable in air at room temperature with loss of crystal water when being heated to 150 °C loss of crystal water; further heating will cause its decomposition. It is insoluble in ethanol but highly soluble in water. 5% aqueous solution has a pH value of 7.6 to 8.6. Rats by intraperitoneal injection: LD50: 1549 mg/kg; ADI without any special provisions (FAOWHO, 1994).
Application	1. It can be used as Ph adjusting agents and emulsifying enhancers applied to jam, candy, jelly and ice cream; its combination with citric acid has an effect of alleviating tour; it also has effects on forming complex with metal ions. China rules that it can be applied to various types of food with appropriate usage according to the absolute necessity. 2. It can be used as a food additive, as complex agent and buffering agent in electroplating industry; at the field of pharmaceutical industry, it is used for the manufacturing of anti-clotting drugs; and used as the detergent additives in light industry. 3. It is used as the analysis agents used for chromatography analysis and can also used for preparing bacterial culture medium; moreover, it can also be applied into pharmaceutical industry. 4. The product can be used for the flavoring processing of food, as stabilizers, buffers and deputy complex-forming agents in non-toxic electroplating industry; at pharmaceutical industry, it is used as anti-clotting agent, phlegm drugs and diuretics drugs. It can also be used in brewing, injection, newspaper and movies medicines.
Production methods	It is produced by the neutralization of citric acid by sodium hydroxide or sodium bicarbonate. Dissolve sodium bicarbonate in water upon stirring and heating; add citric acid, continue to heat up to 85-90 °C; adjust the pH to 6.8; adjust active carbon for bleaching. Filter when the mixture is still hot; condense the filtrate under reduced pressure; cool and the crystal comes out; filter, wash, dry to obtain the final products of sodium citrate. C6H8O7 + 3NaHCO3 → C6H5Na3O7 • 2H2O + 3CO2 ↑ + H2O
Chemical Properties	white powder or colourless crystals
Usage	An anticoagulant also used as a biological buffer
Biological Activity	Commonly used laboratory reagent

Trisodium citrate dihydrate Preparation Products And Raw materials

Raw materials	Sodium hydroxide-->Sulfuric acid -->Sodium carbonate-->Calcium carbonate-->Citric acid-->LIMONIN(SH)
Preparation Products	6-bromo-3,4-dihydro-2H-chromen-4-ol-->Deoxynucleotide-->Thrombin

Details:

Trisodium citrate dihydrate Basic information

Product Name:	Trisodium citrate dihydrate
Synonyms:	1,2,3-Propanetricarboxylicacid,2-hydroxy-,trisodiumsalt,dihydrate;ANTI-BABOON IGM, BIOTIN;BETA-HYDROXY-TRICARBOXYLIC ACID MONOHYDRATE;HYDROXYTRICARBALLYLIC ACID MONOHYDRATE;CITRIC ACID NA3-SALT 2H2O;CITRIC ACID H2O;CITRIC ACID TRISODIUM SALT DIHYDRATE;CITRIC ACID, 3NA, DIHYDRATE
CAS:	6132-04-3
MF:	C6H9Na3O9
MW:	294.1
EINECS:	201-069-1
Product Categories:	INORGANIC & ORGANIC CHEMICALS;FOOD ADDITIVES;Food and Feed Additive;ACS Grade;Biochemicals and Reagents;Biological Buffers;Buffers A to Z;Building Blocks;Carbonyl Compounds;Carboxylic Acid Salts;Chelators;Chemical Synthesis;Essential Chemicals;Inorganic Salts;Organic Building Blocks;Research Essentials;Solutions and Reagents;Food additive and acidulant
Mol File:	6132-04-3.mol

Trisodium citrate dihydrate Chemical Properties

mp	>300 °C(lit.)
density	1.76
FEMA	3026
Fp	173.9 °C
storage temp.	Store at RT.
solubility	H₂O: 100 mg/mL
form	powder
color	white
Water Solubility	720 g/L (25 ºC)
Merck	14,8602
BRN	6104939
Stability:	Stable. Incompatible with bases, reducing agents, oxidizing agents.
CAS DataBase Reference	6132-04-3(CAS DataBase Reference)
EPA Substance Registry System	1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate(6132-04-3)

Safety Information

Hazard Codes	Xi
Risk Statements	37/38-41-36/37/38
Safety Statements	26-36/37/39-24/25-36
WGK Germany	1
RTECS	GE7810000

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

Trisodium citrate dihydrate Usage And Synthesis

General description	Sodium citrate, (molecular formula: Na3C6H5O7 • 2H2O) has molecular weight of 294.1, is a colorless crystal or white crystalline powder product; it is odorless, salty taste, and cool. It will lose its crystal water at 150 °C and will be decomposed at even higher temperature. It also has slight deliquescence in wet air and has weathering property upon hot air. It is soluble in water and glycerol, but insoluble in alcohol and some other organic solvents. Sodium citrate has no toxic effect, and has pH adjusting capability as well as having a good stability, and therefore can be used in the food industry. Sodium citrate has the greatest demand when being used as a food additive; As food additives, it is mainly used as flavoring agents, buffers, emulsifiers, bulking agents, stabilizers and preservatives; in addition, combination between sodium citrate and citric acid can be used in a variety of jams, jelly, juice, drinks, cold drinks, dairy products and pastries gelling agents, flavoring agents and nutritional supplements.
Excellent performance	Sodium citrate is currently the most important citrate. It is produced by two steps: first starch food is fermented to generate citric acid; secondly, citric acid is neutralized by alkali to generate the final products. Sodium citrate has the following excellent performance: (1) Safe and nontoxic properties; Since the basic raw material for the preparation of sodium citrate mainly comes from the food, it is absolutely safe and reliable without causing harm to human health. The United Nations Food and Agriculture and the World Health Organization has no restriction in its daily intake, which means that this product can be considered as non-toxic food. (2) It is biodegradable. After subjecting to the dilution of a large amount of water, sodium citrate is partially converted into citrate, which coexists with sodium citrate in the same system. Citrate is easy to subject to biological degradation at water by the action of oxygen, heat, light, bacteria and microbes. Its decomposition pathways are generally going through aconitic acid, itaconic acid, citraconic acid anhydride to be further converted to carbon dioxide and water. (3) The ability of forming complex with metal ions. Sodium citrate has a good capability of forming complex with some metal ions such as Ca2+, Mg2+; for other ions such as Fe2+, it also has a good complex-forming ability. (4) Excellent solubility, and the solubility increases with increasing temperature of water. (5) It has a good capability for pH adjustment and a good buffering property. Sodium citrate is a weak acid-strong alkali salt; When combined with citrate, they can form a pH buffer with strong compatibility; therefore, this is very useful for some cases in which it is not suitable to have large change of pH value. In addition, sodium citrate also has excellent retardation performance and stability. The above information is edited by the chemicalbook of Dai xiongfeng.
Reference quality standards	British Pharmacopoeia BP98 Edition Quality Item Technical Index Content 99.0-101.0% PH Meet the rule Heavy Metal (PB) ≤ 0.001% Arsenic ≤ 0.0001% Ferric ≤ 0.001% Oxalate ≤ 0.03% Sulfate ≤ 0.015% Readily carbonizable substance Meet the rule Chloride ≤ 0.005% Water 11.0-13.0% Appearance of the solution clear and transparent solution, colorless Pyrogen consistent with the test
Effect and application	During the process of clinically taking fresh blood, adding some amount of sterile sodium citrate can play a role in prevent blood clotting; this is exactly taking advantage of the features that calcium citrate can form soluble complexes with calcium ion; In the field of medicine, it is used for the in vitro anti- clotting drugs and anticoagulants drugs, phlegm drugs, and diuretics drugs during blood transfusions; it can also used for cyanide-free electroplating industry; also used as developer for photographic industry. It can be used as flavoring agents, buffering materials, emulsifiers, and stabilizer in the food industry. Moreover, it is also widely used in chemical, metallurgical industry, the absorption of sulfur dioxide exhaust with the absorption rate of 99% and regenerate liquid sulfur dioxide citrate for recycle application. Sodium citrate has a good water solubility and a excellent cheating capability with Ca2 +, Mg2 + and other metal ions; it is biodegradable and has a strong dispersing ability and anti-redeposition ability; Daily-applied chemical detergents use it as alternative to trimer sodium phosphate for production of non-phosphorus detergent and phosphate-free liquid detergent. Adding a certain amount sodium citrate to the detergent can significantly increase the cleaning ability of detergent cleaning. The large scale of application of sodium tripolyphosphate as a builder in detergents is an important discovery in synthetic detergent industry. It is non-toxic without environmental pollution; it can also be acted as a buffer for the production of cosmetics.
The maximum allowed amount of food additives and maximal permitted residue limits
Chemical Properties	It is colorless crystals or white crystalline powder, and is odorless, cool and salty. It has no melting point with a relative density of 1.857. It is stable in air at room temperature with loss of crystal water when being heated to 150 °C loss of crystal water; further heating will cause its decomposition. It is insoluble in ethanol but highly soluble in water. 5% aqueous solution has a pH value of 7.6 to 8.6. Rats by intraperitoneal injection: LD50: 1549 mg/kg; ADI without any special provisions (FAOWHO, 1994).
Application	1. It can be used as Ph adjusting agents and emulsifying enhancers applied to jam, candy, jelly and ice cream; its combination with citric acid has an effect of alleviating tour; it also has effects on forming complex with metal ions. China rules that it can be applied to various types of food with appropriate usage according to the absolute necessity. 2. It can be used as a food additive, as complex agent and buffering agent in electroplating industry; at the field of pharmaceutical industry, it is used for the manufacturing of anti-clotting drugs; and used as the detergent additives in light industry. 3. It is used as the analysis agents used for chromatography analysis and can also used for preparing bacterial culture medium; moreover, it can also be applied into pharmaceutical industry. 4. The product can be used for the flavoring processing of food, as stabilizers, buffers and deputy complex-forming agents in non-toxic electroplating industry; at pharmaceutical industry, it is used as anti-clotting agent, phlegm drugs and diuretics drugs. It can also be used in brewing, injection, newspaper and movies medicines.
Production methods	It is produced by the neutralization of citric acid by sodium hydroxide or sodium bicarbonate. Dissolve sodium bicarbonate in water upon stirring and heating; add citric acid, continue to heat up to 85-90 °C; adjust the pH to 6.8; adjust active carbon for bleaching. Filter when the mixture is still hot; condense the filtrate under reduced pressure; cool and the crystal comes out; filter, wash, dry to obtain the final products of sodium citrate. C6H8O7 + 3NaHCO3 → C6H5Na3O7 • 2H2O + 3CO2 ↑ + H2O
Chemical Properties	white powder or colourless crystals
Usage	An anticoagulant also used as a biological buffer
Biological Activity	Commonly used laboratory reagent

Trisodium citrate dihydrate Preparation Products And Raw materials

Raw materials	Sodium hydroxide-->Sulfuric acid -->Sodium carbonate-->Calcium carbonate-->Citric acid-->LIMONIN(SH)
Preparation Products	6-bromo-3,4-dihydro-2H-chromen-4-ol-->Deoxynucleotide-->Thrombin

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