TIANFU-CHEM - Imati...

TIANFU-CHEM - Imatinib mesylate

TIANFU-CHEM - Imatinib mesylate

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1 Kilogram

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  • Min.Order :1 Kilogram
  • Purity: 99.0%
  • Payment Terms : L/C,D/A,D/P,T/T,,MoneyGram,Other

Keywords

Imatinib mesylateImatinib mesylate 220127-57-1 C30H35N7O4S

Quick Details

  • Appearance:Off-White Solid
  • Application:Organic synthesis
  • PackAge:IN 25kg drums
  • ProductionCapacity:10|Metric Ton|Month
  • Storage:In Room Temperature
  • Transportation:As per the MSDS

Superiority:

Imatinib mesylate Basic information
a small-molecule inhibitor
Product Name: Imatinib mesylate
Synonyms: GLIVEC;GLEEVEC;IMATINIB METHANESULFONATE;CGP-57148B;4-[(4-methylpiperazin-1-yl)methyl]-n-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide methanesulfonate;4-[(4-methyl-1-piperazinyl)methyl]-n-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide monomethanesulfonate;STI-571;IMATINIB BASE(IMA-3)
CAS: 220127-57-1
MF: C30H35N7O4S
MW: 589.71
EINECS:  
Product Categories: Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;Tyrosine Kinase Inhibitors;Aromatics;Heterocycles;API;Glivec, CGP-57148B, STI-571;Antineoplastic;Anti-cancer&immunity;Inhibitors
Mol File: 220127-57-1.mol
Imatinib mesylate Structure

 

Details:

 
 
Imatinib mesylate Chemical Properties
mp  214-224°C
storage temp.  -20°C Freezer
CAS DataBase Reference 220127-57-1(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xn
Risk Statements  22
Hazardous Substances Data 220127-57-1(Hazardous Substances Data)
MSDS Information
 
 
Imatinib mesylate Usage And Synthesis
a small-molecule inhibitor Imatinib mesylate (also called Gleevec) is a small-molecule inhibitor of the fusion protein Bcr-Abl, the causal agent in chronic myelogenous leukemia.
As an inhibitor of PDGFR, imatinib mesylate appears to have utility in the treatment of a variety of dermatological diseases. Imatinib has been reported to be an effective treatment for FIP1L1-PDGFRalpha+ mast cell disease, hypereosinophilic syndrome, and dermatofibrosarcoma protuberans.
Chemical Properties Off-White Solid
Usage A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL)
Usage Imatinib Mesylate is orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively. Imatinib also known as Gleevec, Glivec, CGP-57148B, STI-571 & Imatinib
Usage Imatinib Mesylate (STI571) is an orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively.
Usage echinocandin antifungal, active against infections with Aspergillus and Candida, inhibits cell wall synthesis

 

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