Tubastatin A

Tubastatin A

Tubastatin A

Min.Order / FOB Price:Get Latest Price

1 Gram

Negotiable

  • Min.Order :1 Gram
  • Purity: More than 98%
  • Payment Terms : T/T

Keywords

Tubastatin A Structure Tubastatin a hydrochloride Structure TubastatinA supplier

Quick Details

  • Appearance:white solid powder
  • Application:Use as research only
  • PackAge:according to the clients requirement
  • ProductionCapacity:10|Kilogram|Month
  • Storage:Store at -20°C
  • Transportation:by sea or by air

Superiority:

1.we are direct manufacturer and we have 7 years experience in this aera.

2.we can provide competitive price for every customer and guarantee the quality of our goods.
3.Specials are possible when client's order is big enough, including the discount policy;
4.we promise we will return your money if our product don't have effect.
5.Our company promise to deliver clients' package to his hands safely, or we'll cover the total loss and reship in time;
6. Our customers may buy our products again after they use our sample.

In stock ,>98% purity with low price. If you need HNMR\HPLC,please contact us!

Details:

Tubastatin A is a potent and selective HDAC6 inhibitor. Demonstrates 1093-fold selectivity over HDAC1 (IC50 values of 15 nM for HDAC6 vs 16.4 µM for HDAC1). Tubastatin A was substantially more selective than the known HDAC6 inhibitor Tubacin at all isozymes except HDAC8. Tubastatin A is a potent HDAC6 inhibitor with an IC50 value of 15 nM. Comparatively, it demonstrates over 1,000-fold selectivity against all other HDAC isoforms (IC50 >16 μM), excluding HDAC8 (IC50= 0.9 μM). Tubastatin A induces α-tubulin hyperacetylation at 2.5 μM in primary cortical neuron cultures. In a model of oxidative stress induced by glutathione depletion, tubastatin A displays dose-dependent neuronal protection of primary cortical neuron cultures at 5-10 μM.

Tianjin Kailiqi Biopharma Technology Co., Ltd, is a professional manufacturer specialized in the production and distribution of active pharmaceutical ingredients and intermediates. Our company has strong R&D ability and production experience to provide the customers new APIs. We specialize in developing innovative processes for the synthesis of a wide range of products. We also undertake custom synthesis and contract manufacturing.if you are interest in,pls contact with me,we also have Lab,specifical in some hard synthesis.

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