- Min.Order :1 Kilogram
- Purity: 99.0%Min
- Payment Terms : L/C,D/A,D/P,T/T,
Keywords
GDC-0068 GDC-0068 1001264-89-6
Quick Details
- Appearance:white powder
- Application:For Organic Synthesis use
- PackAge:As per buyers'
- ProductionCapacity:10|Metric Ton|Month
- Storage:In Room Temperature
- Transportation:BY SEA OR AIR
Superiority:
Product Name: GDC-0068
Synonyms: GDC-0068;GDC-0068(RG7440);RG7440;(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone;Ipatasertib (GDC-0068);Ipatasertib;(S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one;(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone Ipatasertib (GDC-0068)
CAS: 1001264-89-6
MF: C24H32ClN5O2
MW: 457.99618
EINECS:
Product Categories: Inhibitor;PI3K/Akt/mTOR;Inhibitors
Mol File: 1001264-89-6.mol
Details:
GDC-0068 Chemical Properties
density 1.254
Safety Information
MSDS Information
GDC-0068 Usage And Synthesis
Usage DC-0068 is a highly selective pan-Akt inhibitor targeting Akt1, Akt2, and Akt3 with IC50 of 5 nM, 18 nM, and 8 nM, respectively.
Usage (2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone is a highly selective AKT inhibitor targeting Akt1 , Akt2 and Akt3. Studies have shown its use in combination with vemurafenib (V118500), have demonstrated therapeutic value in the treatment of hyperproliferative disorders such as cancer.
You Might Also Like
-
High Grade4-Fluoro-1,3-dioxolan-2-one 114435-02-8 Fast Delivery
CAS NO:114435-02-8
-
N-LAURYLDIETHANOLAMINE 1541-67-9
CAS NO:1541-67-9
-
423-55-2 PERFLUOROOCTYL BROMIDE
CAS NO:423-55-2
-
PENTAMETHYLDISILOXANE 1438-82-0
CAS NO:1438-82-0
-
124-41-4 CH3NaO Sodium methanolate
CAS NO:124-41-4
-
409071-16-5 C2BF2LiO4 Lithium difluoro(oxalato)borate(1-)
CAS NO:409071-16-5
Related Searches
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View