- Min.Order :1 Kilogram
- Purity: 99%
- Payment Terms : L/C,D/A,D/P,T/T,
Keywords
ISOQUINOLINYLSULFONYL METHYLAMINO phenylisoquinolinesulfonicacid
Quick Details
- Appearance:Yellow Solid
- Application:127191-97-3
- PackAge:As required
- ProductionCapacity:100-200|Kilogram|Month
- Storage:?20°C
- Transportation:By air/sea/express
Superiority:
About Certificate
1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)
About Service
1. Quality control, before shipment, free sample for test.
2. Prompt shipment with professional documents
3. Packing as your request, with photo before shipment
4. Mixed containers with different mixed items in one container
About Company
HenNan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.
We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you better with our high - quality products and professional team.
We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.
We welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!
Details:
| Product Name: | KN-62 |
| Synonyms: | KN-62;4-[(2S)-2-[(5-ISOQUINOLINYLSULFONYL)METHYLAMINO]-3-OXO-3-(4-PHENYL-1-PIPERAZINYL)PROPYL] PHENYL ISOQUINOLINESULFONIC ACID ESTER;1-[N,O-BIS-(5-ISOQUINOLINESULFONYL)-N-METHYL-L-TYROSYL]-4-PHENYLPIPERAZINE;(S)-5-ISOQUINOLINESULFONIC ACID 4-(2-[(5-ISOQUINOLINYLSULFONYL)METHYLAMINO]- 3-OXO-3-[4-PHENYL-1-PIPERAZINYL]PROPYL)PHENYL ESTER;1-(N,O-BIS-(5-ISOQUINOLINESULFONYL)-*N-M ETHYL-L-TYR;KN-62 97%;KN-62, 99+%;4-((2S)-2-((5-isoquinolinylsulfonyl)methylamino)-3-oxo-3-(4-phenyl-1-piperazinyl)propyl)phenylisoquinolinesulfonicacid |
| CAS: | 127191-97-3 |
| MF: | C38H35N5O6S2 |
| MW: | 721.84 |
| EINECS: | |
| Product Categories: | Protein Kinase Inhibitors and Activators;Protein Kinase;Inhibitor |
| Mol File: | 127191-97-3.mol |
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| KN-62 Chemical Properties |
| mp | 92-94°C |
| density | 1.388 |
| storage temp. | −20°C |
| solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.93 mg/mL |
| form | solid |
| color | white |
| CAS DataBase Reference | 127191-97-3(CAS DataBase Reference) |
| Safety Information |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| MSDS Information |
| Provider | Language |
|---|---|
| ACROS | English |
| SigmaAldrich | English |
| KN-62 Usage And Synthesis |
| Chemical Properties | Yellow Solid |
| Usage | A specific inhibitor of Ca2+/Calmodulin-dependent protein kinase II |
| Usage | selectively inhibits rat brain Ca2+/cadmodulin-dependent protein kinase II, |
| Biological Activity | Selective, cell-permeable inhibitor of CaM kinase II (IC 50 = 0.9 μ M). Binds directly to the calmodulin binding site of the enzyme. Potent non-competitive antagonist at the P2X 7 receptor (IC 50 = 15 nM). Also available as part of the Mixed Kinase Inhibitor Tocriset™ . |
| KN-62 Preparation Products And Raw materials |
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