ChinaZoledronic Acid powder 99% factory 118072-93-8

Min.Order / FOB Price:Get Latest Price

100 Gram	FOB Price: USD 1.0000

100 Gram

FOB Price: USD 1.0000

Min.Order :100 Gram
Purity: 99%min
Payment Terms : L/C,D/P,T/T,Other

Keywords

118072-93-8 ZOLEDRONATE Zoledronic Acid

Quick Details

Appearance:White crystalline powder
Application:Metabolism Drug; Carcino-Chemotherapeutic Drug
PackAge:on request
ProductionCapacity:10|Metric Ton|Year
Storage:Stored in cool and ventilated warehouse. Kept away from fire and heat source. Handle with care to avoid liquid leakage.
Transportation:BY SEA,AIR

Superiority:

Synonym:	Zoledronate
Application:	A protein kinase C activator with apoptotic effects
CAS Number:	118072-93-8
Purity:	≥99%
Molecular Weight:	272.09
Molecular Formula:	C5H10N2O7P2

Description

Zoledronic acid, one of the most potent nitrogen-containing bisphosphonates, induces anti-proliferative and apoptotic effects on multiple myeloma cell lines in vitro by activating protein kinase C. Zoledronic acid also inhibits proliferation of human foetal osteoblastic cell line (hFOB) with an IC50 of 40 μM. In cultures of freshly isolated rabbit and human osteoclasts zoledronic acid (10-100 μM) induced morphological features similar to apoptosis and Osteoclastogenesis was inhibited with an IC50 of 15 nM.

Details:

Identification test Item	Identification test standard	Test Results
Appearance	White crystalline powder	Complies
Melting Point	239°C	Complies
Heavy metals	≤10PPM	Complies
Limit of Phosphite	≤ 0.2%	0.08%
Total impurity	≤ 0.5%	0.13%
Single impurity	≤ 0.1%	0.04%
Water Content %	5.5~6.5%	5.6%
Assay( Dried)	≥98.0%	99.0%