CasNo.34552-83-5,Fine Chemicals Loperamide hydrochloride CAS:34552-83-5,(34552-83-5) Suppliers

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Purity: 99%
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Loperamide hydrochloride 34552-83-5 Loperamide HCL

Quick Details

Appearance:White crystallized powder
Application:medical intermediate
PackAge:A variety of packing ways for your choice
ProductionCapacity:500|Kilogram|Month
Storage:Kept in a well-closed, light-resistant,dry and cool place
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Details:

Loperamide hydrochloride Basic information

Product Name: Loperamide hydrochloride

Synonyms: LABOTEST-BB LT00134703;LOSERAMIN;LOPERAMIDE HCL;LOPERAMIDE HYDROCHLORIDE;4-(4-CHLOROPHENYL)-4-HYDROXY-N,N-DIMETHYL-ALPHA,

ALPHA-DIPHENYL-1-PIPERIDINBUTYRAMIDE HYDROCHLORIDE;4-(4-CHLOROPHENYL)-4-HYDROXY-N,N-DIMETHYL-ALPHA,ALPHA-DIPHENYL-1-PIPERIDINEBUTANAMIDE HYDROCHLORIDE;

4-(4-chlorophenyl)-4-hydroxy-n,n-dimethyl-alpha,alpha-diphenylpiperidine-1-butyramide monohydrochloride;4-[P-CHLOROPHENYL]-4-HYDROXY-N,N-DIMETHYL-ALPHA,ALPHA-DIPHENYL-1-PIPERIDINEBUTYRAMIDE HYDROCHLORIDE

CAS: 34552-83-5

MF: C29H34Cl2N2O2

MW: 513.5

EINECS: 252-082-4

Product Categories:ACTIVE PHARMACEUTICAL INGREDIENTS;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;Opioid receptor and opioid-like receptor;Amines;Heterocycles;IMODIUM;Other APIs

Loperamide hydrochloride Chemical Properties

mp 223-225°C

storage temp. Store at RT

Merck 5571

CAS DataBase Reference 34552-83-5(CAS DataBase Reference)

Loperamide hydrochloride Usage And Synthesis

Chemical Properties White Solid

Usage Labeled Loperamide, which is used as an antidiarrheal

Usage Ca channel blocker

Biological Activity

High affinity μ -opioid receptor agonist with peripheral selectivity (K i values are 2, 48 and 1156 nM for μ -, δ - and κ -opioid receptors respectively). Antidiarrhoeal and antihyperalgesic agent.

Also a Ca 2+ channel blocker; at low micromolar concentrations it blocks broad spectrum neuronal HVA Ca 2+ channels and at higher concentrations it reduces Ca 2+ flux through NMDA receptor operated channels.