Pyriproxyfen 95737-68-1 The No1 in China

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Pyriproxyfen Usage And Synthesis
A regulator of insect growth Pyriproxyfen is a novel kind of insect growth regulator which was successfully developed by Sumitomo Chemical Industry Co., Ltd (Japan) It has the same effect on the insect as juvenile hormone and has various kinds of effects such as inhibiting the mosquitoes, pupating of the flies larvae and its feathering. Upon being exposed to this drug agent, the larvae of mosquitoes and flies will mostly die in the pupal stage without being able to get into feathering. The duration of this agent will persist up to a month or so. Moreover, it is convenient for using with no odor and is a good kind of drugs for killing of mosquito and fly.
Toxicity According to our pesticide toxicity grading standards, pyriproxyfen belongs to low toxicity pesticides. The acute LD50 of rat subject to oral administration of the original drug acute is larger than 5000 mg/kg body weight. For acute percutaneous administration of rats, the LD50 is larger than 2000 mg/kg body weight. For acute inhalation of rat, the LC50 is larger than13000 mg/m3 (4h). It has slight irritation effect on eye without causing sensitization. Test dose has no mutagenic effect and teratogenic response. The non-effect dose of rats subject to 6-month of feeding study is 400mg/kg body weight. Non-effect dose of rat subject to inhalation within 28 day is 482mg/m3. It is absorbed, distributed and excreted rapidly by animal.
The above information is edited by the Chemicalbook of Dai Xiongfeng.
Instructions Pyriproxyfen can be used for controlling the larvae of mosquitoes and flies and some other pests. For prevention and control of mosquito larvae, apply 20 g of 0.5 % pyriproxyfen granules (active ingredient: 100 mg) per cubic meter directly into the water (water depth should be kept at about 10 cm which is best); for control of housefly larvae, apply 20 to 40 g of 0.5% pyriproxyfen granules (active ingredient 100 ~ 200 mg) per cubic meter for spreading on the surface of the housefly breeding ground. It has excellent inhibitory effect on the larvae of mosquitoes and flies.
Precautions 1. It should be kept in dark, cool place and kept away from fire.
2. Upon contacting with it on the skin, we should use soap and clean water for washing thoroughly.
Toxicity For rat: acute oral administration: LD50> 5000mg/kg; acute percutaneous administration: LD50> 2000mg / kg.
Chemical Properties The pure product is crystal with m.p. being 45 ~ 47 ℃, the vapor pressure being 0.29 × 10-3Pa (20 ℃), and the relative density being 1.23 (20 ℃). Solubility: xylene 50%, hexane: 40%, and methanol: 20%.
Uses 1. It is a kind of benzyl ethers class insect growth regulator and is a kind of juvenile hormone type inhibitor of chitin synthesis. It is characterized by its high efficiency, less medication, long duration, crop safety, low toxicity to fish, and the small impact on the ecological environment. It can be used to control Homoptera, Thysanoptera, Diptera, and Lepidoptera pests. Its inhibitory inhibition on insects is related to its influence on the molting and reproduction of insect. For mosquito class sanitation pests, applying low-dose of this product for 4th instar larvae in late phase that can result in larvae’s death at the pupation stage and inhibition of the formation of adults. For the application, apply the granules directly to the sewage pond or dispersing it in the breeding ground of mosquitoes and flies. It can also be used for prevention of sweetpotato whitefly and scale insects. Pyriproxyfen also has an inner suction transfer activity which can affect the larvae hidden in the back of the blade.
2. It is used for the control of public health pests.
Usage Pyriproxyfen is a pyridine-based pesticide used against a variety of arthropoda, in particular to protect cotton crops against whitefly.