Bromophenyl pyriMidine PD 158780 solution
1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)
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Product Name: | PD158780 |
Synonyms: | N4-(3-Bromophenyl)-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine;Pyrido[3,4-d]pyriMidine-4,6-diaMine,N4-(3-broMophenyl)-N6-Methyl- (Related Reference);Pyrido[3,4-d]pyriMidine-4,6-diaMine,N4-(3-broMophenyl)-N6-Methyl-;PD 158780 solution |
CAS: | 171179-06-9 |
MF: | C14H12BrN5 |
MW: | 330.188 |
EINECS: | |
Product Categories: | |
Mol File: | 171179-06-9.mol |
PD158780 Chemical Properties |
density | 1.611±0.06 g/cm3 (20 ºC 760 Torr) |
storage temp. | Store at -20°C |
PD158780 Usage And Synthesis |
Biological Activity | Potent inhibitor of ErbB receptor family tyrosine kinases (IC 50 values are 0.008, 49 and 52 nM for EGFR, ErbB2 and ErbB2/ErbB4 respectively) that does not inhibit FGF or PDGF-mediated tyrosine phosphorylation. Induces G 1 cell cycle arrest in MCF10A cells and is antiproliferative in A431 human epidermal carcinoma cells. |
PD158780 Preparation Products And Raw materials |
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