Pentamidine isethio...

Pentamidine isethionate
Pentamidine isethionate
Pentamidine isethionate
Pentamidine isethionate

Pentamidine isethionate

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1 Metric Ton

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  • Min.Order :1 Metric Ton
  • Purity: 98%
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Keywords

Pentamidine isethionate 140-64-7 C23H36N4O10S2

Quick Details

  • Appearance:Odorless white or almost white crystals or powder
  • Application:140-64-7
  • PackAge:As requested
  • ProductionCapacity:300|Metric Ton|Day
  • Storage:room temperature
  • Transportation:By air or by sea

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Pentamidine isethionate Basic information
Product Name: Pentamidine isethionate
Synonyms: 1,5-BIS(P-AMIDINOPHENOXY)PENTANE BIS(2-HYDROXYETHANESULFONATE SALT);1,5-BIS[P-AMIDINOPHENOXY]PENTANE BIS[2-HYDROXYETHANESULFONATE SALT] ISETHIONATE SALT;4,4'-(PENTAMETHYLENEDIOXY)DIBENZAMIDE BIS(2-HYDROXYETHANESULFONATE);4,4'-(PENTAMETHYLENEDIOXY)DIBENZAMIDINE, BIS-2-HYDROXYETHANESULFONATE;PENTAMIDINE ISETHIONATE;PENTAMIDINE ISETHIONATE SALT;4,4'-(pentamethylenedioxy)dibenzamidine bis(2-hyd;pentamidine isetionate
CAS: 140-64-7
MF: C23H36N4O10S2
MW: 592.68
EINECS: 205-424-1
Product Categories: API;HIV/AIDS/Related Products;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File: 140-64-7.mol
Pentamidine isethionate Structure
 
Pentamidine isethionate Chemical Properties
mp  188-194 °C(lit.)
storage temp.  −20°C
form  powder
Merck  13,7192
CAS DataBase Reference 140-64-7(CAS DataBase Reference)
EPA Substance Registry System Ethanesulfonic acid, 2-hydroxy-, compd. with 4,4'-[1,5-pentanediylbis( oxy)]bis[benzenecarboximidamide] (2:1)(140-64-7)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38-43
Safety Statements  26-36/37
RIDADR  3249
WGK Germany  3
RTECS  CV6500000
HazardClass  6.1(b)
PackingGroup  III
 
Pentamidine isethionate Usage And Synthesis
Usage Has been widely used as a drug to treat protozoal diseases, such as malaria, amoebic dysentery and trypanosomiasis. It has also been shown to be effective for both prophylaxis of pneumocystic carinii pneumonia (PCC).
Usage Antiparasitic
General Description Odorless white or almost white crystals or powder. Odor also reported as a slight butyric odor. Very bitter taste. pH (5% aqueous solution) 4.5-6.5.
Air & Water Reactions Hygroscopic. May be sensitive to prolonged exposure to air. Aqueous solutions deteriorate on storage. Water soluble.
Reactivity Profile Can decompose on prolonged exposure to light.
Fire Hazard Flash point data for Pentamidine isethionate are not available; however, Pentamidine isethionate is probably combustible.
Biological Activity Antimicrobial. Neuroprotective; inhibits constitutive nitric oxide synthase in the brain and acts as a NMDA glutamate receptor antagonist.

 

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