4-THIOURIDINE 13957-31-8 C9H12N2O5S
4-THIOURIDINE Basic information |
Product Name: | 4-THIOURIDINE |
Synonyms: | THIOURIDINE, 4-;4-THIOURIDINE;thiouridine;4-thiouridineapprox.;4-Thio-D-uridine;4-SH-Ur;NSC 518132;Uridine, 4-thio- |
CAS: | 13957-31-8 |
MF: | C9H12N2O5S |
MW: | 260.27 |
EINECS: | 237-735-3 |
Product Categories: | Biochemicals and Reagents;Nucleoside Analogs;Nucleosides, Nucleotides, Oligonucleotides;Bases & Related Reagents;Nucleotides;Sulfur & Selenium Compounds |
Mol File: | 13957-31-8.mol |
4-THIOURIDINE Chemical Properties |
mp | 139-140℃ (ethanol ) |
storage temp. | −20°C |
form | crystalline |
color | light yellow |
CAS DataBase Reference | 13957-31-8(CAS DataBase Reference) |
Safety Information |
WGK Germany | 3 |
4-THIOURIDINE Usage And Synthesis |
Usage | Nucleotide analogue, essential for cell growth in certain bacterial species. This compound is also able to chelate with certain metal ions, and in tRNA it can act as a built-in antiphotomutagenic agent that protects Escherichia coli cells against mutagenesis. |
Usage | 4-Thiouridine is a photoreactive (crosslinking) uridine analogue that upon phosphorylation to 4-thioUTP may be incorporated into RNA structures. 4-Thiouridine may be used to study the specificity and kinetics of uridine-cytidine kinases. |
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