CALPAIN INHIBITOR III 88191-84-8 C17H17NO3
CALPAIN INHIBITOR III Basic information |
Product Name: | CALPAIN INHIBITOR III |
Synonyms: | CALPAIN INHIBITOR III;CARBOBEZOXY-VALINYL-PHENYLALANINALZ-VAL-PHE-CHO;CARBOBENZOXY-VALINYL-PHENYLALANINAL;MDL 28170;Z-VAL-PHE-ALDEHYDE;Z-VAL-PHE-CHO;MDL 28170, Z-Val-Phe-al;Cbz-L-Val-L-Phe-OH |
CAS: | 88191-84-8 |
MF: | C17H17NO3 |
MW: | 283.32 |
EINECS: | |
Product Categories: | inhibitor |
Mol File: | 88191-84-8.mol |
CALPAIN INHIBITOR III Chemical Properties |
storage temp. | 2-8°C |
solubility | DMSO: 26 mg/mL |
Safety Information |
Safety Statements | 22-24/25 |
WGK Germany | 3 |
CALPAIN INHIBITOR III Usage And Synthesis |
Usage | MDL 28170 acts as a caplain inhibitor reducing hypoxia in ischemic-retinopathy, and various other neuroprotective effects. |
Biological Activity | Potent, selective inhibitor of calpain and cathepsin B (K i values are 10 and 25 nM respectively) that does not inhibit trypsin-like serine proteases. Rapidly penetrates the blood-brain barrier following systemic administration and displays neuroprotective effects in vivo . |
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