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5-[[(1,1'-BIPHENYL)-4-YL]METHYL]-N,N-DIMETHYL-1H-TETRAZOLE-1-CARBOXAMIDE 874902-19-9 C17H17N5O
5-[[(1,1'-BIPHENYL)-4-YL]METHYL]-N,N-DIMETHYL-1H-TETRAZOLE-1-CARBOXAMIDE Basic information |
Product Name: | 5-[[(1,1'-BIPHENYL)-4-YL]METHYL]-N,N-DIMETHYL-1H-TETRAZOLE-1-CARBOXAMIDE |
Synonyms: | LY 2183240;5-[[(1,1'-BIPHENYL)-4-YL]METHYL]-N,N-DIMETHYL-1H-TETRAZOLE-1-CARBOXAMIDE;5-(biphenyl-4-ylMethyl)-N,N-diMethyl-1H-tetrazole-1-carboxaMide;LY-2183240 MN-25;1H-Tetrazole-1-carboxamide, 5-([1,1′-biphenyl]-4-ylmethyl)-N,N-dimethyl-;5-Biphenyl-4-ylmethyl-tetrazole-1-carboxylic acid dimethylamide;N,N-dimethyl-5-[(4-phenylphenyl)methyl]tetrazole-1-carboxamide |
CAS: | 874902-19-9 |
MF: | C17H17N5O |
MW: | 307.34978 |
EINECS: | |
Product Categories: | |
Mol File: | 874902-19-9.mol |
5-[[(1,1'-BIPHENYL)-4-YL]METHYL]-N,N-DIMETHYL-1H-TETRAZOLE-1-CARBOXAMIDE Chemical Properties |
Melting point | 87-88℃ |
density | 1.21 |
storage temp. | Store at +4°C |
5-[[(1,1'-BIPHENYL)-4-YL]METHYL]-N,N-DIMETHYL-1H-TETRAZOLE-1-CARBOXAMIDE Usage And Synthesis |
Biological Activity | Novel and highly potent blocker of anandamide uptake (IC 50 = 270 pM). Inhibits fatty acid amide hydrolase (FAAH) activity (IC 50 = 12.4 nM). Following i.p. administration in rats, increases brain anandamide concentration and exerts antinociceptive effects in formalin model of pain. |
5-[[(1,1'-BIPHENYL)-4-YL]METHYL]-N,N-DIMETHYL-1H-TETRAZOLE-1-CARBOXAMIDE Preparation Products And Raw materials |
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