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Bimatoprost supplier Bimatoprost manufacturer 155206-00-1
Bimatoprost is a potent FP receptor agonist that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma. Bimatoprost is manufactured at Cayman Pharma, our Czech subsidiary. The DMF is on file with the US FDA, Canada, and India.
Bimatoprost is a synthetic amide F2α derivative ,it can selectively simulate the effect forefront amines produced by the body, which make aqueous humor production rate increase aqueous outflow resistance is reduced, by increasing the amount of aqueous outflow of the uveoscleral and trabecular Netcom channel to reduce intraocular pressure (IOP),it is considered to be the most effective hypotensive drug of topical ocular anti-glaucoma drugs,it is suitable for the treatment of open-angle glaucoma (POAG) or invalid elevated intraocular other ocular hypotensive medications compression syndrome (OHT) patients.
A potent prostanoid receptor (FP) agonist and PGF2α analog. Its biological activity is mediated by action on prostamide receptors. Has therapeutic potential for glaucoma and ocular hypertension.
Catalogue Number | B386800 |
Chemical Name | Bimatoprost |
Synonyms | (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-5-heptenamide; AGN-192024; Lumigan; Prostamide; |
CAS Number | 155206-00-1 |
Molecular Formula | C??H??NO? |
Appearance | White to Off-White Solid |
Melting Point | 64 - 65°C |
Molecular Weight | 415.57 |
Storage | Amber Vial, -20°C Freezer, Under Inert Atmosphere |
Solubility | Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly) |
Stability | Light Sensitive |
Category | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | Bimatoprost is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α. |
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