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Synephrine is a kind of biological active substance, mainly extracted from the orange, tangerine peel, green husk and rutaceae plants, is a traditional Chinese medicine and plays an important role of frutus aurantii immaturus effective component, has a strong heart, increase blood volume contraction, blood vessels, high total peripheral vascular resistance and make the left ventricular pressure and the effect of arterial blood pressure, shock resistance, and the effect that reduce weight, but because the Synephrine has the similar structure to that of jute alkali has excited central nervous, the potential side effects of cardiovascular disease, in recent years it is limited to use in the United States, Canada and other countries.
Synephrine (p-synephrine), an alkaloid, is derived from the fruit of small citrus trees . Its tartrate form is synephrine tartrate. Synephrine is related structurally to endogenous neurotransmitters, and acts on several adrenergic and serotonergic receptors. Synephrine has been reported to have thermogenic properties. Therefore, it is widely used as a dietary supplement to enhance energy and promote weight loss. It is reported that the (-)-form
Synephrine, Selective alpha1 adrenoceptor agonist
Selective α1 adrenoceptor agonist
Selective α1 adrenoceptor agonist. Shows vasoconstrictive and antidepressant effects in vivo. Orally active.
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