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high quality of Cyanocobalamine 18195-32-9 98%MIN 18195-32-9 factory
Vitamin B12 consists of a class of chemically-related compounds (vitamers), all of which have vitamin activity. It contains the biochemically rare element cobalt.
Vitamin B12, is used to treat vitamin B12 deficiency, cyanide poisoning, and hereditary deficiency of transcobalamin II. It is also given as part of the schilling test for detecting pernicious anemia.
For cyanide poisoning, a large amount may be given intravenously, and sometimes in combination with sodium thiosulfate. The mechanism of action is straightforward: the hydroxycobalamin hydroxide ligand is displaced by the toxic cyanide ion, and the resulting harmless B12 complex is excreted in urine. In the United States, the Food and Drug Administration approved (in 2006) the use of hydroxocobalamin for acute treatment of cyanide poisoning.
High vitamin B12 level in elderly individuals may protect against brain atrophy or shrinkage, associated with Alzheimer's disease and impaired cognitive function.
High-dose administration of Vitamin B12 has been additionally validated to stimulate the activity of the body's TH1 suppressor T-Cells, which then down-regulates the over-production of the allergen antibody IgE in allergic individuals.
Vitamin B12 is used to treat vitamin B12 deficiency, cyanide poisoning, and hereditary deficiency of transcobalamin II.It is also given as part of the Schilling test for detecting pernicious anemia.
For cyanide poisoning, a large amount may be given intravenously, and sometimes in combination with sodium thiosulfate.The mechanism of action is straightforward: the hydroxycobalamin hydroxide ligand is displaced by the toxic cyanide ion, and the resulting harmless B12 complex is excreted in urine. In the United States, the Food and Drug Administration approved (in 2006) the use of hydroxocobalamin for acute treatment of cyanide poisoning.
High vitamin B12 level in elderly individuals may protect against brain atrophy or shrinkage, associated with Alzheimer's disease and impaired cognitive function.
High-dose administration of Vitamin B12 has been additionally validated to stimulate the activity of the body's TH1 suppressor T-Cells, which then down-regulates the over-production of the allergen antibody IgE in allergic individuals.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Recommended storage temperature: 2 - 8 °C
General Description |
Cyanocobalamin, also known as vitamin B12, is a synthetic form of the essential nutrient that plays a crucial role in the body's production of red blood cells and maintenance of the nervous system. It is commonly used as a dietary supplement for individuals with vitamin B12 deficiency, which can occur due to certain medical conditions, dietary restrictions, or aging. Cyanocobalamin is converted to its active forms, adenosylcobalamin and methylcobalamin, once it is absorbed and utilized by the body. It is available in various forms including oral capsules, injections, and as an ingredient in multivitamin and B-complex supplements. While generally considered safe, high doses of cyanocobalamin may cause side effects such as skin rash, itching, and diarrhea, and individuals allergic to cobalt or cobalamin should avoid its use. |
InChI:InChI=1/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;-1;+2/p-2/t31?,34-,35?,36-,37?,41-,52-,53-,56?,57+,59-,60+,61+,62+;;/m1../s1
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