83-67-0 discount Theobromine factory

Min.Order / FOB Price:Get Latest Price

1 Kilogram	FOB Price: USD 100.0000

1 Kilogram

FOB Price: USD 100.0000

Min.Order :1 Kilogram
Purity: 99.90%
Payment Terms : L/C,D/A,D/P,T/T,

Keywords

Theobromine Theobromine factory 83-67-0 discount

Quick Details

Appearance:solid or liquid
Application:for pharma use
PackAge:drum and bag
ProductionCapacity:5000|Kilogram|Month
Storage:in sealed air resistant place
Transportation:by sea or air

Superiority:

Phosphosdiesterase inhibitor, weak adenosine receptor antagonist, diuretic and smooth muscle relaxant.

Theobromine is a methylxanthine alkaloid and derivative of caffeine that has been found in cocoa beans and has diverse biological activities. It is an adenosine A₁ receptor antagonist Theobromine (150 μg/ml) increases AMPK phosphorylation and inhibits adipocyte differentiation, ERK and JNK phosphorylation, and IL-6 and TNF-α production in 3T3-L1 preadipocytes cultured in differentiation medium. It inhibits decreases in renal cortex SIRT1 activity and increases in NADPH oxidase-dependent reactive oxygen species (ROS) production, as well as reduces kidney hypertrophy and albuminuria in a spontaneously hypertensive rat model of streptozotocin-induced diabetes when administered at a dose of 5 mg/kg per day. Theobromine is toxic to dogs with an LD₅₀ value of 250 to 500 mg/kg.

Details:

Theobromine is a weak PDE (phosphodiesterase) inhibitor and Adenosine A Receptor (adenosine receptor) blocker as well as a diuretic and smooth-muscle relaxant.

Catalogue Number	T343800
Chemical Name	Theobromine
Synonyms	3,7-Dihydro-3,7-dimethyl-1H-purine-2,6-dione; 3,7-Dimethyl-3,7-dihydro-1H-purine-2,6-dione; 3,7-Dimethylxanthine; Diurobromine; NSC 5039; SC 15090; Santheose; Teobromin; Theosalvose; Theostene; Thesal; Theophylline-Ethylenediamine Imp. G (EP)
CAS Number	83-67-0
Molecular Formula	C?H?N?O?
Appearance	White to Off-White Solid
Melting Point	>300°C (dec.)
Molecular Weight	180.16
Storage	Refrigerator
Solubility	Chloroform (Very Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Sonicat
Category	Standards; Food;
Applications	A metabolite of Caffeine.