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PT-141 pharmaceutical peptide pharmaceutical intermediate
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High purity PT-141 Bremelanotide Pepetide CAS: 32780-32-8
Sequence |
Ac-Nle-cyclo(Asp-His-D-Phe-Arg-Trp-Lys-OH) |
One Letter Sequence |
Ac-Nle-cyclo[DH(d-F)RWK] |
Physical Apperance |
White Powder |
Form & Formulations |
Sterile Filtered white lyophilized (freeze-dried) |
Stability |
2 months at room temperature 24 months from date of receipt, 20 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, 20 to 70 °C under sterile conditions after reconstitution. |
Purity |
>98% by RP-HPLC |
Storage |
Lyophilized PT-141 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution PT141 should be stored at 4°C between 2-7 days and for future use be |
PT-141, bremelanotide is experimental and is used for the purpose of sexual arousal. It is a melanocortin based peptide that has shown effectiveness in clinical studies on both male and female rats. Male rats have shown erectile response with doses as low as 1-2 mgs whereas most female rats have shown positive results with higher doses around 2-3 mgs. While the dosage requirements tend to be higher for female rats, the observable results in female rats tend to be stronger. An example of findings among male rats is displayed below in an abstract from this Palatin study:
Bremelanotide or PT-141 is the generic term for a new research peptide for use in helping improve sexual dysfunction in men (erectile dysfunction or impotence) as well as helping improve sexual dysfunction in women (sexual arousal disorder).
Bremelanotide, PT-141 does not act on the vascular system like the former compounds but it is known and has been shown to help increase sexual activity in both male and female mammals. Bremelanotide PT-141 allegedly works by activating melanocortin receptors in the brain, therefore helping increase ones sexual stimulation.
For Research Purpose only, Not for Human Consumption
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