1-(4-Chlorobenzhydryl)piperazine 303-26-4 C17H19ClN2
1-(4-Chlorobenzhydryl)piperazine Basic information |
Product Name: | 1-(4-Chlorobenzhydryl)piperazine |
Synonyms: | 1-((4-chlorophenyl)phenylmethyl)-piperazin;1-(4-Chloro-alpha-phenylbenzyl)piperazine;1-(alpha-Phenyl-4-chlorobenzyl)piperazine;1-(p-chloro-alpha-phenylbenzyl)-piperazin;4-(4-Chlorobenzhydryl)piperazine;Norchlorcyclizine;Piperazine, 1-(alpha-(4-chlorophenyl)benzyl)-;Piperazine, 1-(p-chloro-alpha-phenylbenzyl)- |
CAS: | 303-26-4 |
MF: | C17H19ClN2 |
MW: | 286.8 |
EINECS: | 206-137-4 |
Product Categories: | Heterocycles;Piperazine derivates;API intermediates;Aromatics;Metabolites & Impurities;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Piperazines;PiperazinesHeterocyclic Building Blocks;Intermediates & Fine Chemicals;Pharmaceuticals;C15 to C30;Building Blocks;C16 to C29;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks |
Mol File: | 303-26-4.mol |
1-(4-Chlorobenzhydryl)piperazine Chemical Properties |
Melting point | 65-70 °C(lit.) |
Boiling point | 178-180 °C0.5 mm Hg(lit.) |
Fp | >230 °F |
storage temp. | Refrigerator |
CAS DataBase Reference | 303-26-4(CAS DataBase Reference) |
NIST Chemistry Reference | Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-(303-26-4) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-37/39-24/25 |
WGK Germany | 3 |
RTECS | TL1772000 |
Hazard Note | Irritant |
MSDS Information |
Provider | Language |
---|---|
1-(4-Chlorobenzhydryl)piperazine | English |
SigmaAldrich | English |
ACROS | English |
1-(4-Chlorobenzhydryl)piperazine Usage And Synthesis |
Chemical Properties | White Solid |
Usage | A metabolite of Cetirizine and Hydroxyzine |
Usage | A metabolite of Cetirizine (C281100) and Hydroxyzine. Citirizine impurity A. |
Usage | Cetrizine Dihydrochloride intermediate |
1-(4-Chlorobenzhydryl)piperazine Preparation Products And Raw materials |
Raw materials | Ethyl acetate-->Methanol-->Dichloromethane-->Thionyl chloride-->PETROLEUM ETHER-->Toluene-->Potassium carbonate-->Magnesium sulfate-->Ammonium hydroxide-->1,4-Diazacyclohexane-->Calcium chloride-->Potassium iodide-->2-Butanone-->4-Chlorobenzhydrol |
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