xav-939 284028-89-3 C14H11F3N2OS
xav-939 Basic information |
Product Name: | xav-939 |
Synonyms: | xav-939;3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one;XAV 939/NVP-XAV939;SteMolecule;1,5,7,8-Tetrahydro-2-[4-(trifluoroMethyl)phenyl]-4H-thiopyrano[4,3-d]pyriMidin-4-one;NVP-XAV 939;2-(4-(trifluoromethyl)phenyl)-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-4-ol;XAV 939 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
CAS: | 284028-89-3 |
MF: | C14H11F3N2OS |
MW: | 312.3101496 |
EINECS: | -0 |
Product Categories: | Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds |
Mol File: | 284028-89-3.mol |
xav-939 Chemical Properties |
storage temp. | Store at RT |
xav-939 Usage And Synthesis |
Usage | A tankyrase (TNKS) inhibitor that antagonizes Wnt signaling via stimulation of β-catenin degradation and stabilization of axin. It inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1. |
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