Chlorothiazide 58-94-6 C7H6ClN3O4S2
Chlorothiazide Basic information |
Product Name: | Chlorothiazide |
Synonyms: | 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-, 1,1-dioxide;2h-1,2,4-benzothiadiazine-7-sulfonamide,6-chloro-,1,1-dioxide;Aldoclor;Alurene;Chloriazid;Chlorosal;Chlorothiazid;Chlorthiazide |
CAS: | 58-94-6 |
MF: | C7H6ClN3O4S2 |
MW: | 295.72 |
EINECS: | 200-404-9 |
Product Categories: | Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;DIURIL |
Mol File: | 58-94-6.mol |
Chlorothiazide Chemical Properties |
Melting point | 342-343°C |
storage temp. | 2-8°C |
Water Solubility | <0.1 g/100 mL at 19.5 ºC |
Merck | 2168 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 58-94-6(CAS DataBase Reference) |
NIST Chemistry Reference | Chlorothiazide(58-94-6) |
EPA Substance Registry System | 2H-1,2,4-Benzothiadiazine- 7-sulfonamide, 6-chloro-, 1,1-dioxide(58-94-6) |
Safety Information |
Hazard Codes | Xn |
Risk Statements | 42/43-20/21/22 |
Safety Statements | 36 |
WGK Germany | 2 |
RTECS | DK9450000 |
Hazardous Substances Data | 58-94-6(Hazardous Substances Data) |
Chlorothiazide Usage And Synthesis |
Chemical Properties | Off-White Solid |
Usage | Diuretic; antihypertensive |
Definition | ChEBI: 4H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position is substituted by chlorine and that at position 7 is substituted by a sulfonamide group. A diuretic, it is used for treatment of oedema and hypertension. |
General Description | Crystals; white powder. |
Air & Water Reactions | Insoluble in water. |
Reactivity Profile | Alkaline aqueous solutions will decompose on standing or heating . |
Fire Hazard | Flash point data for Chlorothiazide are not available; however, Chlorothiazide is probably combustible. |
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