Hygromycin B

Hygromycin B
Hygromycin B
Hygromycin B
Hygromycin B

Hygromycin B

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1 Kilogram

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Hygromycin B 31282-04-9 C20H37N3O13

Quick Details

  • Appearance:white powder
  • Application:31282-04-9
  • PackAge:As requested
  • ProductionCapacity:300|Kilogram|Day
  • Storage:2-8°C
  • Transportation:By air or by sea

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Hygromycin B Basic information
Product Name: Hygromycin B
Synonyms: HYGROMYCIN B HYDRATE;HYGROMYCIN B, STREPTOMYCES HYGROSCOPICUS;HYGROMYCIN B, STREPTOMYCES SPECIES;HYGROGOLD(TM);O-6-AMINO-6-DEOXY-L-GLYCERO-D-GALACTOHEPTAPYRANOSYLIDENE-(1,2,3)-O-BETA-D-TALOPYRANOSYL-(1,5)-2-DEOXY-N3-METHYL-D-STREPTAMINE;o-6-amino-6-deoxy-l-glycero-d-galacto-heptopyranosylidene-(1-2-3)-o-beta-d-talopyranosyl-(1-5)-2-deoxy-n3-methyl-d-streptamine;O-6-AMINO-6-DEOXY-L-GLYCERO-D-GALACTO-HEPTOPYRANOSYLIDENE-(1-2-3)-O-BETA-D-TALOPYRANOSYL(1-5)-2-DEOXY-N3-METHYL-D-STREPTAMINE;)-o-beta-d-talopyranosyl-(1-5)-2-deoxy-n-(sup3)-methyl-
CAS: 31282-04-9
MF: C20H37N3O13
MW: 527.52
EINECS: 250-545-5
Product Categories: antibiotic;Inhibitors
Mol File: 31282-04-9.mol
Hygromycin B Structure
 
Hygromycin B Chemical Properties
Melting point  160-180°C
storage temp.  2-8°C
solubility  H2O: 50 mg/mL As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 30 days.
form  powder
Merck  13,4878
 
Safety Information
Hazard Codes  T+,Xn,T
Risk Statements  26/27/28-41-42/43-40-36-23/24/25
Safety Statements  23-26-28-36/37/39-45-22-36-36/37
RIDADR  UN 3462 6.1/PG 1
WGK Germany  3
RTECS  WK2130000
F  19
 
Hygromycin B Usage And Synthesis
Usage antibacterial, anthelmintic; LD50 ip (rat) 63mg/Kg
Usage Hygromycin B, a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome
Usage Hygromycin B is an aminoglycoside and a selective antibiotic agent for the hph gene. Hygromycin B inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S rib osome
Usage Hygromycin B is a trisaccharide aminoglycoside with a terminal cyclitol produced by Streptomyces hygroscopicus, reported by researchers at Eli Lily in the early 1950s. Hygromycin B belongs to the destomycin family of aminoglycosides which contain a unique cyclic structure linking the terminal saccharide. Hygromycin B exhibits broad spectrum antibiotic and anthelmintic activity, and is used as a feed additive for swine and poultry. Hygromycin B inhibits polypeptide synthesis by binding peptidyl-tRNA and preventing translocation by Elongation Factor 2.
General Description Amorphous solid or tan powder.
Air & Water Reactions Water soluble.
Reactivity Profile Weakly basic.
Fire Hazard Flash point data for Hygromycin B are not available; however Hygromycin B is probably combustible.

 

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