Troglitazone

Troglitazone
Troglitazone
Troglitazone

Troglitazone

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1 Kilogram

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  • Min.Order :1 Kilogram
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Keywords

Troglitazone 97322-87-7 C24H27NO5S

Quick Details

  • Appearance:Crystalline Solid
  • Application:97322-87-7
  • PackAge:As requested
  • ProductionCapacity:300|Kilogram|Day
  • Storage:Store at -20°C
  • Transportation:By air or by sea

Superiority:

Troglitazone Basic information
Product Name: Troglitazone
Synonyms: RESULIN(TM);ROMGLIZONE;TROGLITAZONE;2,4-thiazolidinedione,5-((4-((3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2h-1-b;5-(4-(6-hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)thiazolidine-2;ci991;enzopyran-2-yl)methoxy)phenyl)methyl)-;gr92132x
CAS: 97322-87-7
MF: C24H27NO5S
MW: 441.54
EINECS:  
Product Categories: Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;Intracellular receptor;Aromatics;Heterocycles;Sulfur & Selenium Compounds
Mol File: 97322-87-7.mol
Troglitazone Structure
 
Troglitazone Chemical Properties
Melting point  184-186°C
storage temp.  Store at -20°C
solubility  DMSO: 20 mg/mL
form  solid
color  white to yellow
CAS DataBase Reference 97322-87-7(CAS DataBase Reference)
 
Safety Information
Safety Statements  22-24/25
WGK Germany  2
RTECS  XJ5813130
 
Troglitazone Usage And Synthesis
Chemical Properties Crystalline Solid
Usage Troglitazone is an an oral hypoglycemic agent which improves insulin sensitivity and decreases hepatic glucose production. Antidiabetic.
Usage antidiabetic;peroxisome proliferator-activated receptors activator
Biological Activity Selective PPAR γ receptor agonist (EC 50 values are 780 and 555 nM at murine and human PPAR γ receptors respectively). Displays no activity at PPAR α or PPAR δ receptors. Antidiabetic agent; exerts potent glucose-lowering effects in insulin-resistant diabetic mice. Displays anti-invasive effect on human breast cancer cells; reduces migration, adhesion and spreading on fibronectin-coated plates. Also inhibits lamellipodia formation and actin polymerization.
 
Troglitazone Preparation Products And Raw materials
Raw materials p-Hydroxybenzaldehyde-->Trifluoromethanesulfonic anhydride-->2-methylpentane

 

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