PIM447

PIM447

PIM447

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1 Gram

Negotiable

  • Min.Order :1 Gram
  • Purity: 98%
  • Payment Terms : L/C

Keywords

N-[4-[(1R,3S,5S)-3-amino-5-methylcyclohexyl]pyridin-3-yl]-6-(2,6-difluorophenyl)-5-fluoropyridine-2-carboxamide PIM447 CHEMBL3651966

Quick Details

  • Appearance:Powder
  • Application:This active molecular is a potent PIM 1, 2, and 3 kinase inhibitor under the development of Novartis. In vivo, PIM447 reduces the tumor burden and also preventes tumor-associated bone loss in a dissem
  • PackAge:inquiry
  • ProductionCapacity:10|Kilogram|Month
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  • Transportation:inquiry

Superiority:

This active molecular is a potent PIM 1, 2, and 3 kinase inhibitor under the development of Novartis. In vivo, PIM447 reduces the tumor burden and also preventes tumor-associated bone loss in a disseminated murine model of human myeloma. In vitro, it inhibits osteoclast formation and resorption. Moreover, it increases osteoblast activity and mineralization. In May 2016, Novartis completed a phase I trial for Multiple myeloma (Second-line treatment or greater) in Japan. #

Details:

This active molecular is a potent PIM 1, 2, and 3 kinase inhibitor under the development of Novartis. In vivo, PIM447 reduces the tumor burden and also preventes tumor-associated bone loss in a disseminated murine model of human myeloma. In vitro, it inhibits osteoclast formation and resorption. Moreover, it increases osteoblast activity and mineralization. In May 2016, Novartis completed a phase I trial for Multiple myeloma (Second-line treatment or greater) in Japan. #

 

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