PIMOZIDE

PIMOZIDE
PIMOZIDE
PIMOZIDE

PIMOZIDE

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1 Kilogram

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  • Min.Order :1 Kilogram
  • Purity: 98%
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Keywords

PIMOZIDE 2062-78-4 C28H29F2N3O

Quick Details

  • Appearance:powder
  • Application:2062-78-4
  • PackAge:As requested
  • ProductionCapacity:300|Kilogram|Day
  • Storage:2-8°C
  • Transportation:By air or by sea

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PIMOZIDE Basic information
Product Name: PIMOZIDE
Synonyms: PIMOZIDE;1-(1-(4,4-bis(p-fluorophenyl)butyl)-4-piperidyl)-2-benzimidazolinon;1-(1-(4,4-bis(p-fluorophenyl)butyl)-4-piperidyl)-2-benzimidazolinone;1-(4,4-bis(p-fluorophenyl)butyl)-4-(2-oxo-1-benzimidazolinyl)piperidine;mcn-jr-6238;orap;1-[1-(4,4-BIS[4-FLUOROPHENYL]BUTYL)-4-PIPERIDINYL]-1,3-DIHYDRO-2H-BENZ-IMIDAZOL-2-ONE;3-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidyl)-1H-benzimidazol-2-one
CAS: 2062-78-4
MF: C28H29F2N3O
MW: 461.55
EINECS: 218-171-7
Product Categories: Organics;Dopamine receptor;ORAP;Inhibitors
Mol File: 2062-78-4.mol
PIMOZIDE Structure
 
PIMOZIDE Chemical Properties
storage temp.  2-8°C
solubility  DMSO: 18 mg/mL
CAS DataBase Reference 2062-78-4(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36
RIDADR  3249
WGK Germany  3
RTECS  DE1750000
HazardClass  6.1(b)
PackingGroup  III
 
PIMOZIDE Usage And Synthesis
Usage antipsychotic
Usage Used for the suppression of motor and phonic tics in patients with Tourette's Disorder who have failed to respond satisfactorily to standard treatment.
Definition ChEBI: A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which one of the nitrogens is substituted by a piperidin-4-yl group, which in turn is substituted on the nitrogen by a 4,4-bis(p-fluorophen l)butyl group.
Biological Activity Dopamine D 2 -receptor antagonist and antipsychotic which binds with very high affinity to the cloned rat 5-HT 7 receptor (K i = 0.5 nM).

 

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